2-(2-(3-(2-(7-Chloro-2-quinolinyl)-ethenylphenyl)-3-hydroxypropyl)phenyl)-2-propanol Name 2-(2-(3-(2-(7-Chloro-2-quinolinyl)-ethenylphenyl)-3-hydroxypropyl)phenyl)-2-propanol Synonym (s)-1-(3-(2-(7-chloro-2-quinolinyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)-phenyl)propanol
Hubei YuanCheng GongChuang Technology Co.Ltd [2015-06-03 11:15:16 ]
Pexidartinib(PLX-3397) is a small-molecule receptor tyrosine kinase (RTK) inhibitor of KIT, CSF1R and FLT3 with potential antineoplastic activity.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 11:12:36 ]
SU 6656 is a selective inhibitor of Src kinases, Including Src, Yes, Lyn, and Fyn (IC50 = 280, 20, 130, 170 nM, respectively). By comparing PDGF-stimulated tyrosine phosphorylation events in untreated and SU6656-treated cells, we found that some substrates (for example, c-Cbl, an
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 11:08:56 ]
BS-181 is a small molecule inhibitor of CDK7 in a cell-free environment, which displays more potential activity than roscovitine with IC 50 of 510 nM. Among the CDKs and other 69 kinases from many different classes, BS-181 shows high inhibitory selectivity for CDK7, inhibits CDK2
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 11:05:01 ]
Sodium 2,3-dimercapto-1-propanesulfonate Synonyms SULFONIC ACID SODIUM SALT CAS 4076-02-2 MF C3H7NaO3S3 MW 210.27 EINECS 223-796-3 mp 215 °C (dec.) storage temp. 2-8°C Purity 99% Usage API Package 1KG foil bag; 25Kg drum Price us$3833
Hubei YuanCheng GongChuang Technology Co.Ltd [2015-06-03 11:02:07 ]
PLX647 was tested against a panel of 400 kinases at a concentration of 1 μM, 35-fold above its FMS enzymatic IC50 and 60-fold above its KIT enzymatic IC50. In addition to FMS and KIT, the activities of only nine kinases were inhibited by more than 50%. PLX647 potently inhibits t
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 11:01:11 ]
AI-10-49 is a protein-protein interaction inhibitor that selectively binds to CBFβ-SMMHC and disrupts its binding to RUNX1 with a FRET IC50 of 0.26 uM.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 10:58:04 ]
2,2,5,5-TETRAMETHYLTETRAHYDROFURAN-3-ONE Name 2,2,5,5-TETRAMETHYLTETRAHYDROFURAN-3-ONE Synonym 2,2,5,5-Tetramethyldihydro-3(2H)-furanone;3(2H)-Furanone,dihydro-2,2,5,5-tetramethyl-;DIHYDRO-2,2,5,5-TETRAMETHYL-3(2H)-FURANONE;2,2,5,5-TETRAMETHYLTETRAHYDROFURAN-3-ONE;2,2,5,5-Tetrame
Hubei YuanCheng GongChuang Technology Co.Ltd [2015-06-03 10:54:48 ]
Evacetrapib (LY2484595) is a potent and selective inhibitor of CETP with IC50 of 5.5 nM, elevates HDL cholesterol without increases in aldosterone or blood pressure.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 10:53:10 ]
APY0201 is a potent, highly selective, ATP-competitive PIKfyve inhibitor (IC50=5.2 nM) that interrupts the conversion of phosphatidylinositol 3-phosphate (PtdIns3P) to PtdIns(3,5)P2; a unique small molecular IL-12/23 production inhibitor.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 10:50:07 ]
Terbutaline sulfate is a β2-adrenergic receptor agonist; a fast-acting bronchodilator and a tocolytic to delay premature labor.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 10:46:28 ]
Afatinib (BIBW2992) irreversibly inhibits EGFR/HER2 including EGFR(wt) , EGFR(L858R) , EGFR(L858R/T790M) and HER2 with IC50 of 0.5 nM, 0.4 nM, 10 nM and 14 nM in cell-free assays, respectively; 100-fold more active against Gefitinib-resistant L858R-T790M EGFR mutant.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 10:42:45 ]
Afatinib (BIBW2992) irreversibly inhibits EGFR/HER2 including EGFR(wt), EGFR(L858R), EGFR(L858R/T790M) and HER2 with IC50 of 0.5 nM, 0.4 nM, 10 nM and 14 nM, respectively; 100-fold more active against Gefitinib-resistant L858R-T790M EGFR mutant.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 10:39:48 ]
1,4-Dioxaspiro[4.5]decan-8-one Name 1,4-Dioxaspiro[4.5]decan-8-one Synonym 1,4-CYCLOHEXANEDIONE MONOETHYLENE ACETAL;1,4-CYCLOHEXANEDIONE MONOETHYLENE KETAL;1,4-DIOXASPIRO[4.5]DECAN-8-ONE;1,4-DIOXASPIRO[4.5]-8-DECANONE;CYCLOHEXANEDIONE(1,4-) MONOETHYLENE;Cyclohexane-1,4-dione mono
Hubei YuanCheng GongChuang Technology Co.Ltd [2015-06-03 10:38:13 ]
ETHYL 1,3-BENZOTHIAZOLE-2-CARBOXYLATE Name ETHYL 1,3-BENZOTHIAZOLE-2-CARBOXYLATE Synonym RARECHEM AL BI 0472;ETHYL BENZOTHIAZOLE-2-CARBOXYLATE;ETHYL 1,3-BENZOTHIAZOLE-2-CARBOXYLATE;2-Benzothiazolecarboxylicacid,ethylester(6CI,9CI);Benzothiazole-2-carboxylic acid ethyl ester;2-Ben
Hubei YuanCheng GongChuang Technology Co.Ltd [2015-06-03 10:35:50 ]
Adrafinil (CRL-40028, Olmifon), prodrug of modafinil, is a mild central nervous system stimulant drug used to relieve excessive sleepiness and inattention, Adrafinil is believed to serve as an alpha-1 adrenoceptor agonist.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 10:35:50 ]
L-Alpha glycerylphosphorylcholine (alpha-GPC, choline alfoscerate) is a natural choline compound found in the brain and in milk. It is also a parasympathomimetic acetylcholine precursor which may have potential for the treatment of Alzheimer's disease
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 10:29:47 ]
Name (S)-2-AMINOBUTYRAMIDE HYDROCHLORIDE Synonym (S)-2-AMINOBUTYRAMIDE HYDROCHLORIDE (S)-2-AMINOBUTANAMIDE HYDROCHLORIDE (S)-2-AMINOBUTYRAMIDE HCL ABAH LEVETIRACETAM'S INTERMEDIATE (2S)-2-AMINOBUTANAMIDE HYDROCHLORIDE (1 1) 2-AMINOBUTANAMIDE HYDROCHLORIDE (1 1) (L)-2-AMINOBUTYRAM
Hubei YuanCheng GongChuang Technology Co.Ltd [2015-06-03 10:26:17 ]
(R)-[3-(3-Fluoro-4-morpholinophenyl)-2-oxo-5-oxazolidinyl]methyl methanesulfonate Name (R)-[3-(3-Fluoro-4-morpholinophenyl)-2-oxo-5-oxazolidinyl]methyl methanesulfonate Synonym (R)-[3-(3-Fluoro-4-morpholinophenyl)-2-oxo-5-oxazolidinyl]methyl methanesulfonate;(R)-[3-(3-Fluoro-4-Mo
Hubei YuanCheng GongChuang Technology Co.Ltd [2015-06-03 10:24:27 ]
AM095 is an LPA1 receptor antagonist with good oral exposure and antifibrotic activity in rodent models. In vitro, AM095 inhibited GTPγS binding to Chinese hamster ovary (CHO) cell membranes overexpressing recombinant human or mouse LPA1 with IC50 values of 0.98 and 0.73 μM, re
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 10:23:56 ]