SBE13 Hcl is a potent and selective PLK1 with IC50 of 0.2 nM; no inhibition om Aurora A kinase, Plk2 and Plk3. We offer a substantial discount on orders of 5g or more.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 11:21:21 ]
Isopropyl 2-(3-nitrobenzylidene)acetoacetate CAS 39562-25-9 MF C14H15NO5 MW 277.27 Purity 99% Usage API Package 1KG foil bag; 25Kg drum Price us$333.3
Hubei YuanCheng GongChuang Technology Co.Ltd [2015-06-03 11:17:23 ]
Felbamate (FBM) is a potent nonsedative anticonvulsant whose clinical effect may be related to the inhibition of N-methyl-D-aspartate (NMDA) .
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 11:15:50 ]
2-(2-(3-(2-(7-Chloro-2-quinolinyl)-ethenylphenyl)-3-hydroxypropyl)phenyl)-2-propanol Name 2-(2-(3-(2-(7-Chloro-2-quinolinyl)-ethenylphenyl)-3-hydroxypropyl)phenyl)-2-propanol Synonym (s)-1-(3-(2-(7-chloro-2-quinolinyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)-phenyl)propanol
Hubei YuanCheng GongChuang Technology Co.Ltd [2015-06-03 11:15:16 ]
Pexidartinib(PLX-3397) is a small-molecule receptor tyrosine kinase (RTK) inhibitor of KIT, CSF1R and FLT3 with potential antineoplastic activity.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 11:12:36 ]
SU 6656 is a selective inhibitor of Src kinases, Including Src, Yes, Lyn, and Fyn (IC50 = 280, 20, 130, 170 nM, respectively). By comparing PDGF-stimulated tyrosine phosphorylation events in untreated and SU6656-treated cells, we found that some substrates (for example, c-Cbl, an
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 11:08:56 ]
BS-181 is a small molecule inhibitor of CDK7 in a cell-free environment, which displays more potential activity than roscovitine with IC 50 of 510 nM. Among the CDKs and other 69 kinases from many different classes, BS-181 shows high inhibitory selectivity for CDK7, inhibits CDK2
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 11:05:01 ]
Sodium 2,3-dimercapto-1-propanesulfonate Synonyms SULFONIC ACID SODIUM SALT CAS 4076-02-2 MF C3H7NaO3S3 MW 210.27 EINECS 223-796-3 mp 215 °C (dec.) storage temp. 2-8°C Purity 99% Usage API Package 1KG foil bag; 25Kg drum Price us$3833
Hubei YuanCheng GongChuang Technology Co.Ltd [2015-06-03 11:02:07 ]
PLX647 was tested against a panel of 400 kinases at a concentration of 1 μM, 35-fold above its FMS enzymatic IC50 and 60-fold above its KIT enzymatic IC50. In addition to FMS and KIT, the activities of only nine kinases were inhibited by more than 50%. PLX647 potently inhibits t
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 11:01:11 ]
AI-10-49 is a protein-protein interaction inhibitor that selectively binds to CBFβ-SMMHC and disrupts its binding to RUNX1 with a FRET IC50 of 0.26 uM.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 10:58:04 ]
2,2,5,5-TETRAMETHYLTETRAHYDROFURAN-3-ONE Name 2,2,5,5-TETRAMETHYLTETRAHYDROFURAN-3-ONE Synonym 2,2,5,5-Tetramethyldihydro-3(2H)-furanone;3(2H)-Furanone,dihydro-2,2,5,5-tetramethyl-;DIHYDRO-2,2,5,5-TETRAMETHYL-3(2H)-FURANONE;2,2,5,5-TETRAMETHYLTETRAHYDROFURAN-3-ONE;2,2,5,5-Tetrame
Hubei YuanCheng GongChuang Technology Co.Ltd [2015-06-03 10:54:48 ]
Evacetrapib (LY2484595) is a potent and selective inhibitor of CETP with IC50 of 5.5 nM, elevates HDL cholesterol without increases in aldosterone or blood pressure.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 10:53:10 ]
APY0201 is a potent, highly selective, ATP-competitive PIKfyve inhibitor (IC50=5.2 nM) that interrupts the conversion of phosphatidylinositol 3-phosphate (PtdIns3P) to PtdIns(3,5)P2; a unique small molecular IL-12/23 production inhibitor.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 10:50:07 ]
Terbutaline sulfate is a β2-adrenergic receptor agonist; a fast-acting bronchodilator and a tocolytic to delay premature labor.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 10:46:28 ]
Afatinib (BIBW2992) irreversibly inhibits EGFR/HER2 including EGFR(wt) , EGFR(L858R) , EGFR(L858R/T790M) and HER2 with IC50 of 0.5 nM, 0.4 nM, 10 nM and 14 nM in cell-free assays, respectively; 100-fold more active against Gefitinib-resistant L858R-T790M EGFR mutant.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 10:42:45 ]
Afatinib (BIBW2992) irreversibly inhibits EGFR/HER2 including EGFR(wt), EGFR(L858R), EGFR(L858R/T790M) and HER2 with IC50 of 0.5 nM, 0.4 nM, 10 nM and 14 nM, respectively; 100-fold more active against Gefitinib-resistant L858R-T790M EGFR mutant.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 10:39:48 ]
1,4-Dioxaspiro[4.5]decan-8-one Name 1,4-Dioxaspiro[4.5]decan-8-one Synonym 1,4-CYCLOHEXANEDIONE MONOETHYLENE ACETAL;1,4-CYCLOHEXANEDIONE MONOETHYLENE KETAL;1,4-DIOXASPIRO[4.5]DECAN-8-ONE;1,4-DIOXASPIRO[4.5]-8-DECANONE;CYCLOHEXANEDIONE(1,4-) MONOETHYLENE;Cyclohexane-1,4-dione mono
Hubei YuanCheng GongChuang Technology Co.Ltd [2015-06-03 10:38:13 ]
ETHYL 1,3-BENZOTHIAZOLE-2-CARBOXYLATE Name ETHYL 1,3-BENZOTHIAZOLE-2-CARBOXYLATE Synonym RARECHEM AL BI 0472;ETHYL BENZOTHIAZOLE-2-CARBOXYLATE;ETHYL 1,3-BENZOTHIAZOLE-2-CARBOXYLATE;2-Benzothiazolecarboxylicacid,ethylester(6CI,9CI);Benzothiazole-2-carboxylic acid ethyl ester;2-Ben
Hubei YuanCheng GongChuang Technology Co.Ltd [2015-06-03 10:35:50 ]
Adrafinil (CRL-40028, Olmifon), prodrug of modafinil, is a mild central nervous system stimulant drug used to relieve excessive sleepiness and inattention, Adrafinil is believed to serve as an alpha-1 adrenoceptor agonist.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 10:35:50 ]
L-Alpha glycerylphosphorylcholine (alpha-GPC, choline alfoscerate) is a natural choline compound found in the brain and in milk. It is also a parasympathomimetic acetylcholine precursor which may have potential for the treatment of Alzheimer's disease
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 10:29:47 ]
