3-isobutylglutaric acid Name 3-isobutylglutaric acid Synonym 3-(2-methylpropyl)pentanedioic acid; Pentanedioic acid, 3-(2-methylpropyl)-; (±)3-isobutylglutaric acid CAS 75143-89-4 EINECS Assay 99% M F C9H16O4 M W 188.2209 BP 326.197°C at 760 mmHg FP 165.289°C Density 1.126g/cm
Hubei YuanCheng GongChuang Technology Co.Ltd [2015-06-03 13:58:26 ]
3-Thiophenemalonic acid Synonyms LABOTEST-BB LT00112328;3-THIENYLMALONIC ACID;3-THIOPHENEMALONIC ACID;THIOPHENE-3-MALONIC ACID;3-thienyl-propanedioicaci;3-Thienylpropanedioic acid;3-Thiophenemalonic acids;3-TMA CAS 21080-92-2 MF C7H6O4S MW 186.19 EINECS 244-198-9 mp 139 °C (dec.
Hubei YuanCheng GongChuang Technology Co.Ltd [2015-06-03 13:57:48 ]
3-Pyridylacetic acid hydrochloride CAS 6419-36-9 MF C7H8ClNO2 MW 173.6 EINECS 229-148-6 mp 161-163 °C(lit.) Chemical Properties white to beige crystalline powder Purity 99% Usage API Package 1KG foil bag; 25Kg drum Price us$200
Hubei YuanCheng GongChuang Technology Co.Ltd [2015-06-03 13:56:24 ]
Name 2-THIENYL-2-DIMETHYLAMINOETHYL KETONE HCL CAS 5424-47-5 Assay 99% M F C9H14ClNOS M W 219.73 Specific Rotate MP or BP 124.7 ℃ at 760mmHg Density Appearance powder Application Pharmaceutical Raw Material Package 25kg/cardboard drum Standard manufacturer's standard MOQ 1kg Pr
Hubei YuanCheng GongChuang Technology Co.Ltd [2015-06-03 13:55:13 ]
3,5-Di-tert-butylbromobenzene CAS 22385-77-9 MF C14H21Br MW 269.22 mp 62-66 °C(lit.) storage temp. Room temperature. Chemical Properties White solid Purity 99% Usage API Package 1KG foil bag; 25Kg drum Price us$166.6
Hubei YuanCheng GongChuang Technology Co.Ltd [2015-06-03 13:50:36 ]
JSH-23 exhibited inhibitory effect with an IC(50) value of 7.1 microM on nuclear factor (NF)-kappaB transcriptional activity in lipopolysaccharide (LPS)-stimulated macrophages RAW 264.7, and interfered LPS-induced nuclear translocation of NF-kappaB without affecting IkappaB degra
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 13:46:33 ]
2,4-Dihydroxybenzoic acid Name 2,4-Dihydroxybenzoic acid Synonym 4-Hydroxysalicylic acid; beta-Resorcylic Acid; BETA RESORCYLIC ACID; β-Resorcylic acid; 2,4-dihydroxybenzoate CAS 89-86-1 EINECS 201-946-9 Assay 99% M F C7H6O4 M W 154.12 MP 225-227℃ BP 414.8°C at 760 mmHg FP 21
Hubei YuanCheng GongChuang Technology Co.Ltd [2015-06-03 13:42:59 ]
DMH-1 is a potent and selective BMP inhibitor with IC50s of 27/107.9/<5 nM for ALK1/2/3 respectively; inactive on ALK5, BMPR2, AMPK and VEGFR2.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 13:42:54 ]
Name 2,4-DIFLUOROANILINE Synonym 2,4-DIFLUOROBENZENAMINE 1-AMINO-2,4-DIFLUOROBENZENE 2,4-DIFLUORO-BENZENAMINE 2,4-DIFLUORO-ANILIN ANILINE, 2,4-DIFLUORO- BENZENAMINE, 2,4-DIFLUORO- LABOTEST-BB LTBB000653 AKOS 91127 2,4-DIFLUOROPHENYLAMINE CAS 367-25-9 76563-56-9 EINECS 206-687-5 A
Hubei YuanCheng GongChuang Technology Co.Ltd [2015-06-03 13:40:52 ]
Dabrafenib (GSK2118436) is a mutant BRAFV600 specific inhibitor with IC50 of 0.8 nM, with 4- and 6-fold less potency against B-Raf(wt) and c-Raf, respectively.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 13:40:24 ]
6H05 gives the greatest degree of modification, which allosterically modifies the oncogenic G12C mutant of highly homologous protein H-Ras without affecting wild-type K-Ras [1]. 6H05 can be used as an intermediate for the synthesis of other oncogenic K-Ras(G12C) inhibitors.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 13:38:22 ]
LDN193189(DM 3189) is a selective BMP signaling inhibitor, inhibits the transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50 of 5 nM and 30 nM, respectively, exhibits 200-fold selectivity for BMP versus TGF-β
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 13:34:40 ]
AZ20 decreases pChk1 Ser345, pChk1 Ser317 and pChk1 Ser296 levels in a concentration-dependent manner. Prolonged exposure with AZ20 increases H2AX pan-nuclear staining, indicative of replication stress.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 13:30:46 ]
CZC24832 is a selective inhibitor of PI 3-kinase γ (IC50 = 1.0 μM in a PI 3-Kγ-dependent fMLP-induced neutrophil migration assay); exhibits limited off-target effects in kinome profiling of 154 identified lipid and protein kinases and 922 other proteins.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 13:27:07 ]
RKI-1447 inhibits potently ROCK1 and ROCK2 in a dose-dependent manner with IC50 values of 14.5 nM and 6.2 nM, respectively. RKI-1447 suppressed phosphorylation of the ROCK substrates MLC-2 and MYPT-1 in human cancer cells, but had no effect on the phosphorylation levels of the AK
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 13:23:13 ]
SGI-1027 is a potent and selective inhibitor of DNA methyltransferase (DNMT) with IC50 of 6, 8, 7.5 μM for DNMT1, DNMT3A, and DNMT3B, respectively.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 13:18:17 ]
UNC2250 is a phosphorylation of endogenous Mer inhibitor with an IC50 of 9.8 nM and blocked ligand-stimulated activation of a chimeric EGFR-Mer protein.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 13:15:28 ]
AHAS inhibitor is a novel acetohydroxyacid synthase(AHAS) inhibitor, a promising drug target against Mycobacterium tuberculosis (MTB).
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 13:11:21 ]
PF-543 is a novel cell-permeant inhibitor of SphK1 with a Ki of 3.6 nM, PF-543 is sphingosine-competitive and is more than 100-fold selective for SphK1 over the SphK2 isoform.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 13:08:40 ]
Alogliptin benzoate(SYR 322) is a potent, selective inhibitor of DPP-4 with IC50 of <10 nM, exhibits greater than 10,000-fold selectivity over DPP-8 and DPP-9.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 13:05:15 ]