The chemical 2C-H, as well as 2C-I and 2C-B, is a synthesis by the eminent chemist Alexander Shulgin. The drug 2C-H belongs to phenylethylamines, in particular to their group 2C. It is known that if it enters the human body
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LSD (lysergic acid diethylamide), first synthesized in 1938, is an extremely potent hallucinogen. It is synthetically made from lysergic acid, which is found in ergot, a fungus that grows on rye and other grains. It is so potent its doses tend to be in the microgram (mcg) range.
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The oral, targeted synthetic DMARD (tsDMARD) [2] , JAK1 and JAK2 inhibitor baricitinib (Olumiant) is a novel small molecule [1] that is approved in the EU [3] and Japan [4] for the treatment of adults with rheumatoid arthritis RA (moderate or severe active [3] ), who responded in
HangZhou HuiSheng Biotech Pharmaceutical Co., Ltd [2021-06-13 23:13:40 ]
Commercially available ethyl isonipecotate (278) was alkylated with 1-bromo-2-chloroethane in the presence of K2CO3 in acetone to give ethyl 1-(2-chloroethyl)piperidine-4-carboxylate (279). This material was then treated with lithium diisopropylamine (LDA) in THF to affect a tran
HangZhou HuiSheng Biotech Pharmaceutical Co., Ltd [2021-06-13 23:08:59 ]
Eliquis (apixaban), a direct inhibitor of factor Xa (FXa), was approved by the European Commission on May 18, 2011 for prevention of venous thromboembolic events (VTE) in adult patients who have undergone elective hip or knee replacement surgery. The discovery of apixaban was the
HangZhou HuiSheng Biotech Pharmaceutical Co., Ltd [2021-06-13 23:06:12 ]
Rivaroxaban is a pure (S)-enantiomer. It is an odorless, non-hygroscopic, white to yellowish powder. Rivaroxaban is only slightly soluble in organic solvents (e g., acetone, polyethylene glycol 400) and is practically insoluble in water and aqueous media. Rivaroxaban, a FXa inhib
HangZhou HuiSheng Biotech Pharmaceutical Co., Ltd [2021-06-13 23:02:44 ]
