Human ACCN3 Stable Cell Line-CHO

The human ACCN3 gene encodes the pore-forming subunit of ASIC3, a proton-activated, Na+-permeable channel. ASIC3 channels expressed primarily in dorsal root ganglion neurons are therapeutic targets in pain and inflammation. ...

Creative Biogene    [Health & Medical]   [Drugs]   [2017-10-20 04:18:49 ]

Human KCNA4 Stable Cell Line-HEK293

The human KCNA4 gene encodes the pore-forming subunit of Kv1.4, a voltage-gated potassium channel. Kv1.4 channels expressed in neurons are therapeutic targets in neuropathic pain. https://www.creative-biogene.com/Human-KCNA4-Stable-Cell-Line-HEK293-196435-12.html ...

Creative Biogene    [Health & Medical]   [Drugs]   [2017-10-20 04:18:00 ]

Human CACNA1B/CACNB3/CACNA2D1 Stable Cell Line-CHO

The human CACNA1B gene encodes the pore-forming subunit of Cav2.2, the voltage-gated N-type calcium channel. CACNB3 and CACNA2D1 encode auxiliary subunits that modulate gating and pharmacological properties. Cav2.2 channels expressed in CNS neurons are therapeutic targets in ...

Creative Biogene    [Health & Medical]   [Drugs]   [2017-10-20 04:17:10 ]

Human CACNA1H/CACNB2/CACNA2D1/KCNJ2 Stable Cell Line-HEK293

The human CACNA1H gene encodes the pore-forming subunit of Cav3.2, a voltage-gated T-type calcium channel. Coexpression with the beta 2 and alpha2delta1 auxiliary subunits recapitulates function in heterologous expression (HEK cells). Inclusion of the inwardly rectifying ...

Creative Biogene    [Health & Medical]   [Drugs]   [2017-10-20 04:16:12 ]

Human GABRA5/GABRB3/GABRG2 Stable Cell Line-HEK293

The human GABRA5, GABRB3, and GABRG2 genes encode a GABA-activated, chloride-selective channel. GABAA receptors expressed in neurons are sites of action for benzodiazepines, barbiturates, and neurosteroids; and therapeutic targets in treatment of several neurological disorders ...

Creative Biogene    [Health & Medical]   [Drugs]   [2017-10-20 04:13:45 ]

Human HCN2 Stable Cell Line-CHO

The human HCN2 gene encodes the pore-forming subunit of a hyperpolarization-activated, cyclic nucleotide-modulated cation channel. HCN2 channels contribute to pacemaker current that controls rhythmic excitation in the heart and brain. ...

Creative Biogene    [Health & Medical]   [Drugs]   [2017-10-20 04:12:50 ]

Human HCN4 Stable Cell Line-HEK293

The human HCN4 gene encodes the pore-forming subunit of a hyperpolarization-activated, cyclic nucleotide-modulated cation channel. HCN4 channels are the predominant HCN isoform in the sinoatrial node and contribute to pacemaker current that controls rhythmic activity in the ...

Creative Biogene    [Health & Medical]   [Drugs]   [2017-10-20 04:12:11 ]

Human KCNN1 Stable Cell Line-CHO

The KCNN1 gene encodes the pore-forming subunit of a small-conductance (2 - 3 pS single channel conductance), K+-selective, channel that is activated by increased intracellular [Ca2+]. Expressed in neurons, hKCa2.1 channels contribute to the afterhyperpolarization that ...

Creative Biogene    [Health & Medical]   [Drugs]   [2017-10-20 04:11:21 ]

Human KCNMA1 Stable Cell Line-CHO

The human KCNMA1 gene encodes the pore-forming subunit of KCa1.1, a calcium-activated BK potassium channel. KCa1.1 channels, widely distributed, are therapeutic targets in stroke, seizure, urinary incontinence, asthma, hypertension, gastric dysmotility, schizophenia, and ...

Creative Biogene    [Health & Medical]   [Drugs]   [2017-10-20 04:10:39 ]

Human KCND3/KCNIP2 Stable Cell Line-CHO

The human KCND3 gene encodes the pore-forming subunit of Kv4.3, a voltage-gated potassium channel. KCNIP2 encodes an auxiliary subunit of the channel. Kv4.3/KChIP2.2 channels expressed in heart are therapeutic targets in atrial fibrillation. ...

Creative Biogene    [Health & Medical]   [Drugs]   [2017-10-20 04:06:11 ]

Human KCNQ1/KCNE1 Stable Cell Line-CHO

The human KCNQ1 gene encodes the pore-forming subunit of Kv7.1, a voltage-gated potassium channel. KCNE1 encodes an auxiliary subunit that modulates gating and pharmacological characteristics. Kv7.1/KCNE1 channels expressed in heart are safety targets in cardiac long-QT risk ...

Creative Biogene    [Health & Medical]   [Drugs]   [2017-10-20 04:01:57 ]

Human KCNQ2/KCNQ3 Stable Cell Line-HEK293

The human KCNQ2 and KCNQ3 genes encode the pore-forming subunits of Kv7.2 and Kv7.3, respectively. These subunits form heteromeric voltage-gated potassium channels that underlie M-current that regulates repetitive neuronal activity. Mutations in KCNQ2 or KCNQ3 that reduce ...

Creative Biogene    [Health & Medical]   [Drugs]   [2017-10-20 04:01:18 ]

Rat Chrm4 Stable Cell Line-CHO

Muscarinic acetylcholine receptors are relatively abundant and mediate many of the diverse actions of acetylcholine in the CNS, as well as throughout non-nervous tissues innervated by the parasympathetic nervous system. There are five muscarinic receptor subtypes referred to as ...

Creative Biogene    [Health & Medical]   [Drugs]   [2017-10-20 03:59:07 ]

Human CHRNA7 Stable Cell Line-CHO

The human CHRNA7 gene encodes the acetylcholine-activated, cationic-selective, nAChRalpha7 channel, expressed in CNS neurons and non-neuronal cells (placenta, endothelia, vascular smooth muscle). The nAChRalpha7 channel is a therapeutic target in treatment of inflammation, ...

Creative Biogene    [Health & Medical]   [Drugs]   [2017-10-20 03:58:31 ]

Human KCNQ3/KCNQ5 Stable Cell Line-HEK293

The human KCNQ3 and KCNQ5 genes encode the pore-forming subunits of Kv7.3 and Kv7.5, respectively. These subunits form heteromeric voltage-gated potassium channels that underlie M-current that regulates repetitive activity in neurons. Mutations in KCNQ3 that reduce M-current ...

Creative Biogene    [Health & Medical]   [Drugs]   [2017-10-20 03:57:54 ]

Human SCN8A Stable Cell Line-CHO

The human SCN8A gene encodes the pore-forming subunit of Nav1.6, a voltage-gated sodium channel expressed in central and peripheral nervous systems. Mutations in the mouse ortholog cause ataxia and other movement disorders. Nav1.6 channels are therapeutic targets in multiple ...

Creative Biogene    [Health & Medical]   [Drugs]   [2017-10-20 03:55:00 ]

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We could give you: 1. Best quality in your requirement 2. Competitive price in China market 3. mature Technical support 4. Professional logistic support 5 . Full experience of large numbers containers loading in Chinese sea port 6 Fast shipment by reputed shipping line 7. ...

Qianqiu Biological Technology Co.    [Health & Medical]   [Drugs]   [2017-09-26 08:01:31 ]

A-PHP Crystal for sell

The best quality in research chemicals. We source the highest quality products and work hand in hand with a variety of major international laboratories,We are ready to sell minimum quantities and large supplies of our product worldwide,ensuring the research chemicals you order ...

researchchem    [Health & Medical]   [Drugs]   [2017-09-25 19:45:51 ]

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Apparance: white crystals Application: Pharmaceutical intermediates DeliveryTime: within 24 hours PackAge: packed in plastic bag or aluminum foil bag Port: china ProductionCapacity: 1000 Kilogram/Month Purity: 99% Storage:keep in dry and cool place Transportation: by air,by ...

Qianqiu Biological Technology Co.    [Health & Medical]   [Drugs]   [2017-09-20 06:57:35 ]

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Product Name:MAF CAS No.:1715016-75-3 Appearance:Powder Purity:99.8% Package: 1kg/Aluminum foil bag or as customer\'s requirements. Storage: Kept in a cool, dry and ventilated place Application: For chemical research Origin: Shanghai Production Capacity: 1000 Kilograms/Month ...

Qianqiu Biological Technology Co.    [Health & Medical]   [Drugs]   [2017-09-20 06:43:28 ]