Pazopanib CAS NO. 444731-52-6

Product Name: Pazopanib CAS NO. 444731-52-6

Synonyms: 5-[[4-[(2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino]pyrimidin-2-yl]amino]-2-methylbenzenesulfonamide;GW 786034;Benzenesulfonamide,5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methyl-;Votrient;

CAS :444731-52-6

Molecular Formula: C21H23N7O2S

Molecular Weight: 437.52

Boiling Point:728.814 °C at 760 mmHg

Flash Point: 394.572 °C

Appearance: White or off white crystal powder

Assay: >99.0%

Package: Aluminum bag

Storage: Room temperature

Application: Pazopanib, with its trade name of Votrient, is one kind of potent and selective multi-targeted receptor tyrosine kinase inhibitor of VEGFR-1, VEGFR-2, VEGFR-3, PDGFR-a/β, and c-kit that blocks tumor growth and inhibits angiogenesis. For being one oral angiogenesis inhibitor targeting VEGFR and PDGFR, Pazopanib has been approved for renal cell carcinoma and soft tissue sarcoma. What's more, Pazopanib may also be active in ovarian cancer, and pazopanib also appears effective in the treatment of non-small cell lung carcinoma.