1. Tianeptine Hemisulfate Monohydrate CAS No.: 1224690-84-9 98.0% purity min. Antidepressant
2.Product parameters
Product name | Tianeptine Hemisulfate Monohydrate |
Other name | tianeptinesulfate; (Thiazepin-11-ylAmino)HeptanoicAcidSemisulfateMonohydrateTianeptineSemisulfateMonohydrate; 7-[(3-Chloro-6,11-dihydro-6-methyl-5,5-dioxidodibenzo[c,f][1,2]thiazepin-11-yl)amino]heptanoicacidsulfatehydrate(2:1:2); Tianeptinehemisulfatemonohydrate(THM); 7-[(3-Chloro-6-methyl-5,5-dioxido-6,11-dihydrodibenzo[c,f][1,2]thiazepin-11-yl)amino]heptanoicacidsulfatehydrate(2:1:2); Tianeptinehemisulfatehydrate;Thiazepin-11-ylAmino)HeptanoicAcidSemisulfate; THM |
CAS No. | 1224690-84-9 |
Molecular formula | C21H27ClN2O8S2 |
Molecular weight | 535.02 |
Purity | 98.0% |
Appearance | White crystal powder |
Application | Dietary Supplement Raw Material |
3.Product introduction
Tianeptine Hemisulfate Monohydrate is a selective serotonin reuptake inhibitor (SSRI) and an antidepressant drug. As a non-traditional antidepressant, its mechanism of action is different from that of traditional antidepressants, improving mood and emotional state by enhancing synaptic plasticity of hippocampal neurons. Tianeptine Hemisulfate Monohydrate is also used to treat anxiety and mood disorders.
Tianeptine Hemisulfate Monohydrate is widely used in medical research, especially in the development of antidepressants. It is also being researched for use in neurodegenerative diseases, pain management, and addiction treatment. The efficacy of Tianeptine Hemisulfate Monohydrate has been widely studied and confirmed, and it has been approved for the treatment of depression in multiple countries.
It should be noted that while Tianeptine Hemisulfate Monohydrate has been proven to be an effective antidepressant in clinical applications, it is classified as a controlled substance in some countries, with restrictions on its use and sale. Anyone using or purchasing Tianeptine Hemisulfate Monohydrate should be aware of the relevant laws and regulations in their country.
4.Features
(1) Unique mechanism of action: Tianeptine Hemisulfate Monohydrate is a selective serotonin reuptake enhancer (SSRE), which means it enhances the reuptake of serotonin in the brain, leading to increased synaptic plasticity and mood improvement. This mechanism of action is different from traditional antidepressants, which are usually serotonin reuptake inhibitors (SSRIs).
(2) Rapid onset of action: Tianeptine Hemisulfate Monohydrate has a fast onset of action, with clinical studies showing improvements in depressive symptoms as early as one week after treatment initiation.
(3) Improved cognitive function: Tianeptine Hemisulfate Monohydrate has been shown to improve cognitive function in patients with major depressive disorder, such as memory and attention.
(4) Low addiction potential: Unlike other antidepressants, Tianeptine Hemisulfate Monohydrate has a low addiction potential and does not cause withdrawal symptoms when discontinued. This is because it does not target the dopamine system, which is associated with addiction and dependence.
(5) Treatment of anxiety disorders: Tianeptine Hemisulfate Monohydrate has been shown to have anxiolytic effects, making it a potential treatment for anxiety disorders such as generalized anxiety disorder and social anxiety disorder.
5.Applications
Tianeptine Hemisulfate Monohydrate is a widely used pharmaceutical chemical in clinical and research fields. As an antidepressant drug, it has been approved in multiple countries for the treatment of depression, anxiety, mood disorders, and other related illnesses. In addition, Tianeptine Hemisulfate Monohydrate has been studied for its potential in treating neurodegenerative diseases such as Alzheimer's, pain management, and addiction treatment.
In recent years, Tianeptine Hemisulfate Monohydrate has gained increasing popularity in medical research, especially in the development of antidepressant drugs. With more studies confirming its therapeutic effects, its application prospects are gradually becoming apparent. Tianeptine Hemisulfate Monohydrate may become a multi-functional drug for treating various neurological disorders in the future.
Moreover, Tianeptine Hemisulfate Monohydrate also has potential applications in other fields. A recent study showed that Tianeptine Hemisulfate Monohydrate may have the potential to treat post-stroke neurofunctional disorders. Additionally, some studies suggest that Tianeptine Hemisulfate Monohydrate may be beneficial for metabolic diseases such as obesity and diabetes.
N-Acetyl-L-cysteine Ethyl Ester and Mental Health: Can It Improve Cognitive Function ?
N-acetyl-L-cysteine ethyl ester (NACET) is a modified form of the amino acid cysteine and has potent antioxidant, hepatoprotective, neuroprotective and anti-inflammatory properties. Its ability to increase glutathione production, protect the liver, regulate neurotransmitters and reduce inflammation makes it a promising compound in health and medicine. NACET, on the other hand, is the ethyl ester derivative of NAC, which is thought to increase the bioavailability and overall effectiveness of NAC as a cognitive enhancer. Overall N-acetyl-L-cysteine ethyl ester shows great promise in promoting overall health and addressing various health conditions.
What isN-Acetyl-L-cysteine Ethyl Ester
N-Acetyl-L-cysteine ethyl ester, commonly known as NACET or N-acetylcysteine ethyl ester, is a modified form of the amino acid L-cysteine. It is derived from N-acetylcysteine (NAC) by adding an ethyl ester group. L-cysteine occurs naturally in foods such as eggs, poultry, and dairy products. NACET is known for its powerful antioxidant properties and is used as a dietary supplement to support overall health and well-being.
NACET is widely recognized for its ability to increase glutathione levels in the body. Glutathione is a major antioxidant and important molecule for various cellular processes. It helps neutralize harmful free radicals and protects our cells from oxidative stress. By increasing glutathione levels, NACET effectively strengthens the body's antioxidant defense system.
NACET increases glutathione levels, supports liver health, and has shown potential to enhance cognitive performance. With its enhanced bioavailability, NACET provides an effective option for individuals seeking to support overall health and well-being.
How Does it Work?
Oxidative stress occurs when there is an imbalance between free radicals and antioxidants in the body. Free radicals are highly reactive molecules that can damage cells and contribute to the development of a variety of diseases, including heart disease and neurodegenerative diseases. NACET helps protect the body from oxidative stress.
Glutathione is one of the most potent antioxidants naturally produced by the body. Plays a vital role in the detoxification process and immune system function. NACET promotes overall health and well-being by increasing glutathione levels and enhancing glutathione production to help the body eliminate toxins and harmful substances more efficiently.
NACET may help regulate levels of neurotransmitters in the brain, such as dopamine and glutamate, which play crucial roles in mood regulation and addiction.
The benefits of N-Acetyl-L-cysteine Ethyl Ester
1. Powerful antioxidant properties
NACET has powerful antioxidant capabilities, and its antioxidant properties make it an excellent supplement for individuals seeking to prevent cell damage caused by oxidative stress. Among them, antioxidants neutralize harmful free radicals in our bodies, protecting our cells from damage and reducing the risk of chronic disease. By fighting oxidative stress, NACET can help promote healthy aging, support heart health, and help strengthen the immune system.
2. Mental health
NACET's role in mental health is receiving increasing attention. Research suggests this compound may have anti-inflammatory properties that can have a positive impact on brain health. Additionally, by promoting the synthesis of glutathione, an important antioxidant, NACET helps reduce neuronal damage and may help improve cognitive function. Some studies even suggest that NACET may help treat mood disorders such as depression and anxiety.
3. Liver support and detoxification
Our liver is responsible for detoxifying harmful substances in the body. NACET shows promise in promoting liver health by supporting detoxification processes and reducing oxidative stress in the liver. By enhancing glutathione production, NACET helps eliminate toxins, potentially protecting the liver from damage and supporting its overall function.
4. Improve cognitive function
Many studies have investigated the effects of NACET on cognitive functions, including memory, attention, and executive functions. A randomized controlled trial conducted by a team of researchers found that NACET supplementation significantly improved cognitive performance and working memory in healthy adults.
It is believed that NACET's beneficial effects on cognitive function may be attributed to its ability to regulate glutamate levels in the brain. Glutamate is an important neurotransmitter involved in learning and memory processes. By regulating glutamate levels, NACET enhances communication between brain regions, thereby improving cognitive function.
Additionally, research suggests that NACET may have neuroprotective properties that may help improve cognitive function. It has been studied for its potential in treating neurodegenerative diseases such as Alzheimer's and Parkinson's disease.
Sources ofN-Acetyl-L-cysteine Ethyl Ester
1. Food sources:
While natural food sources do not contain significant amounts of N-acetyl-L-cysteine ethyl ester, they do contain cysteine, which is converted to NACET in the body. Foods rich in cysteine include poultry, eggs, dairy products, beans, garlic, onions, broccoli and Brussels sprouts. Incorporating these foods into your diet can help ensure an adequate supply of cysteine, which supports the production of NACET in the body.
2. Dietary supplements:
Supplements are another reliable way to obtain N-acetyl-L-cysteine ethyl ester. You can find NACET supplements in many forms, including capsules, tablets, or powder. It is important to note that before adding any new supplements to your daily routine, it is recommended to consult with a healthcare professional to ensure that it is compatible with your current health condition.
Is NAC ethyl ester better than NAC?
Learn about NAC:
N-Acetyl Cysteine, commonly known as NAC, is a powerful antioxidant and precursor to glutathione, the body’s primary antioxidant. With its powerful ability to scavenge free radicals and support the liver, NAC is popular for its numerous health benefits. From respiratory health to liver detoxification, NAC has become the go-to supplement for individuals aiming to enhance their overall health.
The rise of NAC ethyl ester:
NAC ethyl ester is a derivative of NAC and is being developed as a potential upgrade from its predecessor. The esterification process changes the molecular structure of NAC, increasing its bioavailability and promoting superior tissue penetration.
Bioavailability and Absorption:
A key factor in comparing NAC and NAC ethyl ester is their bioavailability and absorption rate. NAC can face challenges in crossing biological barriers and reaching therapeutic levels to effectively clear toxins and protect cells. In comparison, NAC ethyl ester is more bioavailable and can be better absorbed and utilized in the body. This improved delivery mechanism may lead to greater benefits when targeting specific health problems.
Glutathione Recovery Efficiency:
The main purpose of supplementing NAC is to promote the production of glutathione in the body. Glutathione plays a key role in cellular defense against oxidative stress and supports a variety of body processes. While NAC is recognized for its ability to increase glutathione levels, research suggests that NAC ethyl ester may surpass NAC in this regard. The enhanced absorption of NAC ethyl ester may help restore glutathione levels more effectively, providing enhanced cellular protection.