2\'-Deoxynucleosides are modified nucleosides that are essential building blocks of the DNA molecule. They are similar to ribonucleosides (or simply nucleosides), but differ in that they contain a hydrogen atom instead of a hydroxyl group at the 2\' position of the ribose sugar. This chemical modification makes the sugar moiety of 2\'-deoxynucleosides more stable than that of ribonucleosides.
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