SPIRONOLACTONE 52-01-7
Product Quick Detail
- FOB Price
- USD $100.00 / Piece
- Place Of Origin
- China (Mainland)
- Minimum Order
- 1
- Packaging
- N/A
- Delivery
- 15 Days
Specifications
Basic information of Spironolactone 52-01-7
- Product Name: Spironolactone
- Molecular Formula: C24H32O4S
- Molecular Weight: 416.57
- CAS No.: 52-01-7
- Appearance: White powder
- Specifications: EP8/USP38
Usage of Spironolactone 52-01-7
- Treat for High blood pressure
- Treat for primary hyperaldosteronism.
- Treat for Hypokalemia (Potassium deficiency
- Severe heart failure
- Edema (fluid retention) from various conditions, including Congestive edema; Liver cirrhosis ascites; renal edema
- As cosmetic, Spironolactone have an effect in hair grow.
COA of Spironolactone 52-01-7
| ITEMS | STANDARDS | RESULTS |
| Appearance (Ph.Eur.) | A white or yellowish-white powder | White powder |
| Solubility (Ph.Eur.) | Practically insoluble in water, soluble in ethanol (96%) | Complies |
| Identification | ||
|
A. IR–spectrum (Ph.Eur.)
A. IR–spectrum (USP) B. TLC (Ph.Eur.) B. UV absorption (USP) C. Colour reaction (Ph.Eur.) C. Precipitate reaction (USP) |
Meet the requirement
Meet the requirement Meet the requirement Meet the requirement Meet the requirement Meet the requirement |
Complies
Complies Complies Complies Complies Complies |
|
Loss on drying
(Ph.Eur.) (USP) |
Not more than 0.5% Not more than 0.5% |
0.24% 0.23% |
|
Specific optical rotation
(Ph.Eur.) (USP) |
-41°~-46° -41°~-45° |
-43.4° -44.3° |
| Sulphated ash (Ph.Eur.) | ≤0.1% | 0.02% |
| Related substances (Ph.Eur.) | ||
|
Impurity A
Impurity B Impurity C Impurity D Impurity E Impurity I Any unspecified impurity Total |
≤0.2%
≤0.3% ≤0.2% ≤0.15% ≤0.3% ≤0.5% ≤0.10% ≤0.7% |
N.D.
N.D. N.D. N.D. N.D. 0.07% Complies 0.16% |
| Ordinary impurities (USP) | ≤2.0% | Complies |
| Free thiol compounds (Ph.Eur.) | ≤0.05mL | Complies |
| Free mercapto compounds (USP) | ≤0.10mL | Complies |
| Chromium (Ph.Eur.) | ≤50ppm | Complies |
|
Assay
HPLC (Ph.Eur.) HPLC (USP) |
97.5%~102.0% 97.5%~103.0% |
100.2% 99.8% |
|
Residual solvent (In-house)
Methanol Tetrahydrofuran DMF |
≤3000ppm ≤720ppm ≤880ppm |
56ppm ≤LOD (0.0046ppm) ≤LOD (0.23ppm) |
| Particle size (In-house) | 95%≤ 20 microns | Complies |
| Conclusion | Compiles with EP8/USP38 |
- Sinoway Industrial Co., Ltd.
- Tel:+86-0592-5854962
- Fax:+86-0592-5854960
- Email:xie@china-sinoway.com
- WEB:http://www.china-sinoway.com/products/spironolactone-powder-52-01-7.html
- Country: China (Mainland)
- Business Type: Manufacturer
- Market:Africa
- Founded Year:1987
- Address:Floor 16, Huicheng Business Center, No. 839, Xiahe Rd., Siming Dist. Xiamen, Fujian, China
- Contact:Sinoway Sinoway
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