SPIRONOLACTONE 52-01-7
Product sourcing details
- FOB Price
- USD $100.00 / Piece
- Place of Origin
- China (Mainland)
Supplier: Sinoway Industrial Co., Ltd.
Purchasing information
- Minimum order
- 1
- Lead time
- 15 Days
Please confirm with the supplier: Model / reference, Key specifications / compatibility, Samples, Export markets, Supply capacity.
Specifications
Basic information of Spironolactone 52-01-7
- Product Name: Spironolactone
- Molecular Formula: C24H32O4S
- Molecular Weight: 416.57
- CAS No.: 52-01-7
- Appearance: White powder
- Specifications: EP8/USP38
Usage of Spironolactone 52-01-7
- Treat for High blood pressure
- Treat for primary hyperaldosteronism.
- Treat for Hypokalemia (Potassium deficiency
- Severe heart failure
- Edema (fluid retention) from various conditions, including Congestive edema; Liver cirrhosis ascites; renal edema
- As cosmetic, Spironolactone have an effect in hair grow.
COA of Spironolactone 52-01-7
ITEMS | STANDARDS | RESULTS |
Appearance (Ph.Eur.) | A white or yellowish-white powder | White powder |
Solubility (Ph.Eur.) | Practically insoluble in water, soluble in ethanol (96%) | Complies |
Identification | ||
A. IR–spectrum (Ph.Eur.) A. IR–spectrum (USP) B. TLC (Ph.Eur.) B. UV absorption (USP) C. Colour reaction (Ph.Eur.) C. Precipitate reaction (USP) | Meet the requirement Meet the requirement Meet the requirement Meet the requirement Meet the requirement Meet the requirement | Complies Complies Complies Complies Complies Complies |
Loss on drying (Ph.Eur.) (USP) | Not more than 0.5% Not more than 0.5% | 0.24% 0.23% |
Specific optical rotation (Ph.Eur.) (USP) | -41°~-46° -41°~-45° | -43.4° -44.3° |
Sulphated ash (Ph.Eur.) | ≤0.1% | 0.02% |
Related substances (Ph.Eur.) | ||
Impurity A Impurity B Impurity C Impurity D Impurity E Impurity I Any unspecified impurity Total | ≤0.2% ≤0.3% ≤0.2% ≤0.15% ≤0.3% ≤0.5% ≤0.10% ≤0.7% | N.D. N.D. N.D. N.D. N.D. 0.07% Complies 0.16% |
Ordinary impurities (USP) | ≤2.0% | Complies |
Free thiol compounds (Ph.Eur.) | ≤0.05mL | Complies |
Free mercapto compounds (USP) | ≤0.10mL | Complies |
Chromium (Ph.Eur.) | ≤50ppm | Complies |
Assay HPLC (Ph.Eur.) HPLC (USP) | 97.5%~102.0% 97.5%~103.0% | 100.2% 99.8% |
Residual solvent (In-house) Methanol Tetrahydrofuran DMF | ≤3000ppm ≤720ppm ≤880ppm | 56ppm ≤LOD (0.0046ppm) ≤LOD (0.23ppm) |
Particle size (In-house) | 95%≤ 20 microns | Complies |
Conclusion | Compiles with EP8/USP38 |
- Sinoway Industrial Co., Ltd.
- Tel:+86-0592-5854962
- Fax:+86-0592-5854960
- Email:xie@china-sinoway.com
- WEB:http://www.china-sinoway.com/products/spironolactone-powder-52-01-7.html
- Company: Sinoway Industrial Co., Ltd.
- Country: China (Mainland)
- Business Type: Manufacturer
- Market: Africa
- Founded Year: 1987
- Address: Floor 16, Huicheng Business Center, No. 839, Xiahe Rd., Siming Dist. Xiamen, Fujian, China
- Contact: Sinoway Sinoway
