Nintedanib esylate (BIBF 1120 esylate) is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β with IC50 of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/65 nM.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 09:46:36 ]
ARRY-438162 (625 nM) inhibits in vitro osteoclast differentiation with IC50 of 39 nM. ARRY-438162 (10 μM) inhibits in vitro osteoclast resorption with IC50 of 625 nM. ARRY-438162 (2 μM) weakly affects osteoblast differentiation. ARRY-438162 is a recently disclosed potent and se
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 09:37:50 ]
BKM120 is a n orally bioavailable specific oral inhibitor of the pan-class I phosphatidylinositol 3 kinase (PI3K) family of lipid kinases with potential antineoplastic activity. Buparlisib specifically inhibits class I PIK3 in the PI3K/AKT kinase (or protein kinase B) signaling p
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 09:32:15 ]
Daclatasvir (BMS-790052; EBP 883) is a first-in-class, highly-selective oral HCV NS5A inhibitor. We do not have so much in stock right now. If you are in need of them, please hurry up.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 09:28:35 ]
Cabozantinib is a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM, respectively .
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 09:18:31 ]
Cabozantinib S-malate is a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM, respectively.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 09:14:30 ]
Cediranib (AZD2171) is a highly potent VEGFR(KDR) inhibitor with IC50 of <1 nM, also inhibits Flt1/4 with IC50 of 5 nM/≤3 nM, similar activity against c-Kit and PDGFRβ, 36-, 110-fold and >1000-fold selective more for VEGFR than PDGFR-α, CSF-1R and Flt3.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-02 15:00:50 ]
Cerdulatinib (PRT-062070) is an oral active, multi-targeted tyrosine kinase inhibitor with IC50 of 12 nM/6 nM/8 nM/0.5 nM and 32 nM for JAK1/JAK2/JAK3/TYK2 and Syk , respectively. Also inhibits 19 other tested kinases with IC50 less than 200 nM
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-02 14:58:25 ]
Chenodeoxycholic Acid (CDCA), is a hydrophobic primary bile acid that activates nuclear receptors(FXR) involved in cholesterol metabolism.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-02 14:55:33 ]
Coluracetam(MKC-231) is a new choline uptake enhancer.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-02 14:52:15 ]
Crizotinib is inhibitor of the c-Met kinase and the NPM-ALK.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-02 14:47:48 ]
Eletriptan hydrobromide is a orally active, selective 5-HT1B/1D receptor agonist Eletriptan hydrobromide produces a dose-dependent reduction in carotid artery blood flow in vivo. Displays antimigraine activity.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-02 14:44:43 ]
EMD 1214063 is a potent and selective c-Met inhibitor with IC50 of 4 nM, >200-fold selective for c-Met than IRAK4, TrkA, Axl, IRAK1, and Mer
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-02 14:41:33 ]
LGX818 is an orally available mutated BRaf V600E inhibitor(IC50=0.3 nM) with potential antineoplastic activity.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-02 14:38:51 ]
EPZ-5676 is a potent and selective aminonucleoside inhibitor of DOT1L histone methyltransferase with Ki of 80 pM; demonstrating >37,000-fold selectivity against all other PMTs tested, inhibits H3K79 methylation in tumor.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-02 14:36:23 ]
Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-02 14:33:11 ]
Product Description ZKKL High Quality Ipl Hair Removal Machine adopts advanced technology, bipolar Radio Frequency and IPL, for skin rejuvenation, hair removal and speckle removal. Application : High Quality Ipl Hair Removal Machine Hair removal. Skin rejuvenation. Speckle remo
Wuhan CAS Keli Electrooptical Technology Co.Ltd [2015-06-01 16:46:53 ]
Hot selling fashionable Sublimationblank phone caseNexus Google4 E960 Model GN-04 Material PC hard plastic phone Case + Sublimation Aluminum metal Insert/metal sheet Double Sided Adhesive Tape already stick on the back of phone case before ship out,so that will save your time to
SUBTRANSFER TECHNOLOGY CO., LIMITED [2015-06-01 10:20:03 ]
Non sparking tools aluminum bronze alloy combination plier lineman 1.non sparking lineman plier 2.aluminum bronze alloy 3.die forged processing 4.own factory 5.ISO9001 certification
HEBEI TUOKAI SAFETY TOOLS CO.,LTD [2015-06-01 09:24:29 ]
Non sparking tools aluminum bronze alloy adjustablecombination plier 1.non sparking combination plier 2.aluminum bronze material 3.die forged processing 4.our own factory 5.ISO9001 certification
HEBEI TUOKAI SAFETY TOOLS CO.,LTD [2015-06-01 09:22:06 ]