2-Chloro-6-methyl-3-pyridinecarbonitrile Name 2-Chloro-6-methyl-3-pyridinecarbonitrile Synonym BUTTPARK 153\57-09;IFLAB-BB F3250-0678;AKOS BBS-00008244;2-CHLORO-3-CYANO-6-METHYLPYRIDINE;2-CHLORO-6-METHYL-3-PYRIDINECARBONITRILE;2-CHLORO-6-METHYLNICOTINONITRILE;TIMTEC-BB SBB006618;
Hubei YuanCheng GongChuang Technology Co.Ltd [2015-06-03 11:30:53 ]
MLN9708 immediately hydrolyzed to MLN2238, which is an N-capped dipeptidyl leucine boronic acid and preferentially bound to and inhibited the 20S proteasome with an IC50 value of 3.4 nM (Ki = 0.93 nM).
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 11:30:36 ]
Name 2-CHLORO-3-CYANOPYRIDINE Synonym Decanoicaciddimethylamide N,N-Dimethylcapylamide CAS 6602-54-6 EINECS 229-550-1 Assay 99% M F C6H3ClN2 M W 138.56 MP 104-106℃ BP 257.6℃ at 760 mmHg Density 1.33g/cm3 Appearance White powder crystal Application Pharmaceutical Raw Material
Hubei YuanCheng GongChuang Technology Co.Ltd [2015-06-03 11:30:03 ]
Name 3-AMINO-2-CHLORO-4-METHYLPYRIDINE Synonym 2-CHLORO-3-AMINO-4-METHYLPYRIDINE 2-CHLORO-3-AMINO-4-METHYL PYRIDINE 3-AMINO-2-CHLORO-4-METHYLPYRIDINE 2-CHLORO-4-METHYLPYRIDIN-3-AMINE 3-CHLORO-2-METHYLPYRIDIN-4-AMINE 4-AMINO-3-CHLORO-2-PICOLINE 2-METHYL-3-CHLORO-4-AMINOPYRIDINE 3-
Hubei YuanCheng GongChuang Technology Co.Ltd [2015-06-03 11:29:23 ]
AEE788(NVP-AEE 788) is a potent inhibitor of EGFR and HER2/ErbB2 with IC50 of 2 nM and 6 nM, less potent to VEGFR2/KDR, c-Abl, c-Src, and Flt-1, does not inhibit Ins-R, IGF-1R, PKCα and CDK1.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 11:24:23 ]
SBE13 Hcl is a potent and selective PLK1 with IC50 of 0.2 nM; no inhibition om Aurora A kinase, Plk2 and Plk3. We offer a substantial discount on orders of 5g or more.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 11:21:21 ]
2-[(4-Carboxymethylphenoxy)methyl]benzoic acid Name 2-[(4-Carboxymethylphenoxy)methyl]benzoic acid Synonym BENZENE ACETIC ACID, 4-[(2-CARBOXYPHENYL)METHOXY];2-((4-(carboxymethyl)phenoxy)methyl)benzoic acid; CAS 55453-89-9 Assay 99% M F C16H14O5 M W 286.28 Specific Rotate FP 194.7
Hubei YuanCheng GongChuang Technology Co.Ltd [2015-06-03 11:19:23 ]
2-C-Methyl-D-ribono-1,4-lactone CAS 492-30-8 MF C6H10O5 MW 162.14 mp 150-160°C storage temp. -20°C Freezer Chemical Properties White to Off-White Solid Usage Used in synthesis of enantiomerically pure 4-substituted riboses; also for preparing saccharinic acids and lactones via
Hubei YuanCheng GongChuang Technology Co.Ltd [2015-06-03 11:18:46 ]
Felbamate (FBM) is a potent nonsedative anticonvulsant whose clinical effect may be related to the inhibition of N-methyl-D-aspartate (NMDA) .
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 11:15:50 ]
2-(2-(3-(2-(7-Chloro-2-quinolinyl)-ethenylphenyl)-3-hydroxypropyl)phenyl)-2-propanol Name 2-(2-(3-(2-(7-Chloro-2-quinolinyl)-ethenylphenyl)-3-hydroxypropyl)phenyl)-2-propanol Synonym (s)-1-(3-(2-(7-chloro-2-quinolinyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)-phenyl)propanol
Hubei YuanCheng GongChuang Technology Co.Ltd [2015-06-03 11:15:16 ]
Pexidartinib(PLX-3397) is a small-molecule receptor tyrosine kinase (RTK) inhibitor of KIT, CSF1R and FLT3 with potential antineoplastic activity.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 11:12:36 ]
SU 6656 is a selective inhibitor of Src kinases, Including Src, Yes, Lyn, and Fyn (IC50 = 280, 20, 130, 170 nM, respectively). By comparing PDGF-stimulated tyrosine phosphorylation events in untreated and SU6656-treated cells, we found that some substrates (for example, c-Cbl, an
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 11:08:56 ]
BS-181 is a small molecule inhibitor of CDK7 in a cell-free environment, which displays more potential activity than roscovitine with IC 50 of 510 nM. Among the CDKs and other 69 kinases from many different classes, BS-181 shows high inhibitory selectivity for CDK7, inhibits CDK2
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 11:05:01 ]
5-chloro-2,3-difluoropyridine Name 5-chloro-2,3-difluoropyridine EINECS 410-090-7 Molecular Formula C5H2ClF2N CAS 89402-43-7 Synonyms 2,3-DIFLUORO-5-CHLOROPYRIDIN; 2,3-DIFLUORO-5-CHLOROPYRIDINE; 5-Chloro-2,3-Difluoropyridine96%; 2,3-Difluoro-5-Chloro; 2,3-Difulor-5-Chloropyridin
Hubei YuanCheng GongChuang Technology Co.Ltd [2015-06-03 11:02:51 ]
PLX647 was tested against a panel of 400 kinases at a concentration of 1 μM, 35-fold above its FMS enzymatic IC50 and 60-fold above its KIT enzymatic IC50. In addition to FMS and KIT, the activities of only nine kinases were inhibited by more than 50%. PLX647 potently inhibits t
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 11:01:11 ]
AI-10-49 is a protein-protein interaction inhibitor that selectively binds to CBFβ-SMMHC and disrupts its binding to RUNX1 with a FRET IC50 of 0.26 uM.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 10:58:04 ]
Indazole-3-carboxylic acid CAS 4498-67-3 MF C8H6N2O2 MW 162.15 EINECS 224-794-5 mp 266-270 °C (dec.) storage temp. Refrigerator Chemical Properties yellow crystal Usage Indole derivatives useful in treatment of pain and inflammation Purity 99% Usage API Package 1KG foil bag; 25K
Hubei YuanCheng GongChuang Technology Co.Ltd [2015-06-03 10:53:16 ]
Evacetrapib (LY2484595) is a potent and selective inhibitor of CETP with IC50 of 5.5 nM, elevates HDL cholesterol without increases in aldosterone or blood pressure.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 10:53:10 ]
Tricyclo[3.3.1.13,7]decane-1-carboxylicacid Name Tricyclo[3.3.1.13,7]decane-1-carboxylicacid EINECS 212-584-6 Molecular Formula C11H16O2 CAS 828-51-3 Synonyms 1-Adamantanecarboxylicacid (6CI,7CI,8CI); 1-Adamantane-1-carboxylic acid; 1-Carboxyadamantane; Adamantoic acid; 1-Admant
Hubei YuanCheng GongChuang Technology Co.Ltd [2015-06-03 10:51:17 ]
APY0201 is a potent, highly selective, ATP-competitive PIKfyve inhibitor (IC50=5.2 nM) that interrupts the conversion of phosphatidylinositol 3-phosphate (PtdIns3P) to PtdIns(3,5)P2; a unique small molecular IL-12/23 production inhibitor.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 10:50:07 ]
