Baricitinib

The oral, targeted synthetic DMARD (tsDMARD)[2], JAK1 and JAK2 inhibitor baricitinib (Olumiant) is a novel small molecule[1] that is approved in the EU[3] and Japan[4] for the treatment of adults with rheumatoid arthritis RA (moderate or severe active[3]), who responded ...

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Umeclidinium bromide

Commercially available ethyl isonipecotate (278) was alkylated with 1-bromo-2-chloroethane in the presence of K2CO3 in acetone to give ethyl 1-(2-chloroethyl)piperidine-4-carboxylate (279). This material was then treated with lithium diisopropylamine (LDA) in THF to affect a ...

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Apixaban

Eliquis (apixaban), a direct inhibitor of factor Xa (FXa), was approved by the European Commission on May 18, 2011 for prevention of venous thromboembolic events (VTE) in adult patients who have undergone elective hip or knee replacement surgery. The discovery of apixaban was ...

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Rivaroxaban

Rivaroxaban is a pure (S)-enantiomer. It is an odorless, non-hygroscopic, white to yellowish powder. Rivaroxaban is only slightly soluble in organic solvents (e.g., acetone, polyethylene glycol 400) and is practically insoluble in water and aqueous media. Rivaroxaban, a FXa ...

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Rosuvastatin

Known as an antilipemic agent, rosuvastatin belongs to the class of medications called statins, which is primarily used in the treatment of dyslipidemia, including high cholesterol and related conditions. It functions by blocking the enzyme that helps make cholesterol in the ...

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Sulfobutyl Ether Beta-Cyclodextrin (Injection Grade)

β-Cyclodextrin, sulfobutyl ethers, sodium salts is a cyclic oligosaccharide containing seven D-(t)- glucopyranose units attached by α(1→4) glucoside bonds. Sulfobutylether b-cyclodextrin is an anionic bcyclodextrin derivative with a sodium sulfonate salt separated from the ...

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METHYL SALICYLATE

Natural material is found in wintergreen oil, oil of wintergreen, birch oil, green tea seed oil, clove oil, Quercetin tree oil, tuberose oil, small when medicated oil, tea oil, ylang ylang oil and cherry, apple, strawberry fruit juice. It is colorless or pale yellow, red or ...

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metformin HCL

Metformin hydrochloride is a biguanide oral hypoglycemic agent , also known as Glucophage, its hypoglycemic effect is weaker than phenformin, the main role is to reduce the glucagon secretion of A cells ,and to promote the conversion of glucose to glycogen, its characteristic ...

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FEBUXOSTAT

Febuxostat, a selective xanthine oxidase inhibitor, was launched for the chronic management of hyperuricemia in patients with gout. Hyperuricemia is defined as a serum uric acid concentration exceeding the limit of solubility. It predisposes affected persons to gout, a disease ...

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Crisaborole

Crisaborole is a phosphodiesterase- 4 (PDE4) inhibitor that was approved by the USFDA for the treatment of mild to moderate atopic dermatitis (AD) in patients aged two years and older. The drug, which was developed by Anacor Pharmaceuticals and later acquired and marketed by ...

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GABAPENTIN

GABAPENTIN C9H17NO2 60142-96-3 Epilepsy: monotherapy or adjunctive therapy of focal seizures with or without secondary generalization. Recommendations summarized from NICE (2012) Seizure types: adjunctive (focal seizures), contraindicated (generalized tonic- clonic seizures ...

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ERLOTINIB HCL

ERLOTINIB HCL 183321-74-6 C22H23N3O4 The small molecule compound, Erlotinib is a receptor tyrosine kinase inhibitor (EGFR antagonist) and belongs to molecular targeted therapy Drugs. It can inhibit the phosphorylation reaction through competing with adenosine triphosphate to ...

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Cabazitaxel

Cabazitaxel 183133-96-2 C45H57NO14 Cabazitaxel is a semisynthetic taxane derivative that acts as a microtubule inhibitor. It binds to tubulin, promoting the assembly of tubulin into microtubules and inhibiting their disassembly, which results in microtubule stabilization, the ...

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Abacavir

Abacavir 136470-78-5 C14H18N6O The drug is extensively metabolized via stepwise phosphorylation to 5′-mono-, di-, and triphosphate. Abacavir is well absorbed (>75%) and penetrates the CNS. The drug can be taken without regard to meals. The drug does not show any clinically ...

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TENOFOVIR

TENOFOVIR C9H14N5O4P 147127-20-6 Tenofovir disoproxil (Viread) is the first nucleotide analogue approved by the American FDA to treat HIV-1 infections. Tenofovir disoproxil is a drug used in the AIDS cocktail treatment method, and research shows that it has the ability to ...

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TICAGRELOR

TICAGRELOR C23H28F2N6O4S 274693-27-5 Ticagrelor, a new platelet aggregation inhibitor successfully developed by AstraZeneca (U.S.), is the world’s first reversible combination orally-administered P2Y12 adenosine diphosphate receptor antagonist. It is used to reduce ...

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Favipiravir

Favipiravir C5H4FN3O2 259793-96-9 Favipiravir is a broad-spectrum antiviral drug that was cleared by the Drugs Controller General of India (DCGI) last week for “emergency restricted” use among Covid-19 patients. Glenmark will sell the generic favipiravir under the brand name ...

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Mecobalamin

Mecobalamin C63H91CoN13O14P 13422-55-4 Mecobalamin as vitamin B12 derivatives, should be called \"methyl vitamin B12\" according to the chemical structure of name, the functional groups of methylation can be involved in the biochemical process of methyl transfer activity, ...

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SUCRALOSE

SUCRALOSE C12H19C13O8 56038-13-2 Sucralose, 1,6-dichloro-1,6-dideoxy-β-D-fructofuranosyl- 4-chloro-4-deoxy-α-D-galactopyranoside, is a trichloro-galactosucrose sweetener developed by the British sugar company Tate & Lyle during the 1970s (U.S. Pat. 4,343,934 (Aug. 10, 1982), ...

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Remdesevir

Remdesevir C27H35N6O8P 1809249-37-3 Anti-Covid API, In house, GMP-SITE High-quality products and reliable service for every client. :Room 403,Jinsha Century Building,No.900 Jinsha Avenue,Xiasha Economic and Technical Development Zone,Hangzhou,Zhejiang Province,China 310018. ...

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