Pharmaceutical Chemicals Manufacturers and Suppliers
3-FLUORO-4-MORPHOLIN-4-YL-PHENYLAMINE Name 3-FLUORO-4-MORPHOLIN-4-YL-PHENYLAMINE Synonym AKOS B033533;3-FLUORO-4-(4-MORPHOLINYL)-BENZEAMINE;3-FLUORO-4-(4-MORPHOLINYL)-BENZENAMINE;3-FLUORO-4-MORPHOLIN-4-YL-PHENYLAMINE;3-FLUORO-4-MORPHOLIN-ANILINE;3-FLUORO-4-MORPHOLINOANILINE;3-FLU
Hubei YuanCheng GongChuang Technology Co.Ltd [2015-06-03 13:59:29 ]
3-isobutylglutaric acid Name 3-isobutylglutaric acid Synonym 3-(2-methylpropyl)pentanedioic acid; Pentanedioic acid, 3-(2-methylpropyl)-; (±)3-isobutylglutaric acid CAS 75143-89-4 EINECS Assay 99% M F C9H16O4 M W 188.2209 BP 326.197°C at 760 mmHg FP 165.289°C Density 1.126g/cm
Hubei YuanCheng GongChuang Technology Co.Ltd [2015-06-03 13:58:26 ]
3-Pyridylacetic acid hydrochloride CAS 6419-36-9 MF C7H8ClNO2 MW 173.6 EINECS 229-148-6 mp 161-163 °C(lit.) Chemical Properties white to beige crystalline powder Purity 99% Usage API Package 1KG foil bag; 25Kg drum Price us$200
Hubei YuanCheng GongChuang Technology Co.Ltd [2015-06-03 13:56:24 ]
Name 2-THIENYL-2-DIMETHYLAMINOETHYL KETONE HCL CAS 5424-47-5 Assay 99% M F C9H14ClNOS M W 219.73 Specific Rotate MP or BP 124.7 ℃ at 760mmHg Density Appearance powder Application Pharmaceutical Raw Material Package 25kg/cardboard drum Standard manufacturer's standard MOQ 1kg Pr
Hubei YuanCheng GongChuang Technology Co.Ltd [2015-06-03 13:55:13 ]
JSH-23 exhibited inhibitory effect with an IC(50) value of 7.1 microM on nuclear factor (NF)-kappaB transcriptional activity in lipopolysaccharide (LPS)-stimulated macrophages RAW 264.7, and interfered LPS-induced nuclear translocation of NF-kappaB without affecting IkappaB degra
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 13:46:33 ]
DMH-1 is a potent and selective BMP inhibitor with IC50s of 27/107.9/<5 nM for ALK1/2/3 respectively; inactive on ALK5, BMPR2, AMPK and VEGFR2.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 13:42:54 ]
6H05 gives the greatest degree of modification, which allosterically modifies the oncogenic G12C mutant of highly homologous protein H-Ras without affecting wild-type K-Ras [1]. 6H05 can be used as an intermediate for the synthesis of other oncogenic K-Ras(G12C) inhibitors.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 13:38:22 ]
LDN193189(DM 3189) is a selective BMP signaling inhibitor, inhibits the transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50 of 5 nM and 30 nM, respectively, exhibits 200-fold selectivity for BMP versus TGF-β
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 13:34:40 ]
AZ20 decreases pChk1 Ser345, pChk1 Ser317 and pChk1 Ser296 levels in a concentration-dependent manner. Prolonged exposure with AZ20 increases H2AX pan-nuclear staining, indicative of replication stress.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 13:30:46 ]
CZC24832 is a selective inhibitor of PI 3-kinase γ (IC50 = 1.0 μM in a PI 3-Kγ-dependent fMLP-induced neutrophil migration assay); exhibits limited off-target effects in kinome profiling of 154 identified lipid and protein kinases and 922 other proteins.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 13:27:07 ]
RKI-1447 inhibits potently ROCK1 and ROCK2 in a dose-dependent manner with IC50 values of 14.5 nM and 6.2 nM, respectively. RKI-1447 suppressed phosphorylation of the ROCK substrates MLC-2 and MYPT-1 in human cancer cells, but had no effect on the phosphorylation levels of the AK
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 13:23:13 ]
SGI-1027 is a potent and selective inhibitor of DNA methyltransferase (DNMT) with IC50 of 6, 8, 7.5 μM for DNMT1, DNMT3A, and DNMT3B, respectively.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 13:18:17 ]
UNC2250 is a phosphorylation of endogenous Mer inhibitor with an IC50 of 9.8 nM and blocked ligand-stimulated activation of a chimeric EGFR-Mer protein.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 13:15:28 ]
AHAS inhibitor is a novel acetohydroxyacid synthase(AHAS) inhibitor, a promising drug target against Mycobacterium tuberculosis (MTB).
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 13:11:21 ]
PF-543 is a novel cell-permeant inhibitor of SphK1 with a Ki of 3.6 nM, PF-543 is sphingosine-competitive and is more than 100-fold selective for SphK1 over the SphK2 isoform.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 13:08:40 ]
ML347(DN193719) is a highly selective ALK1/ALK2 inhibitor with IC50s of 46/32 nM; shows >300-fold selectivity for ALK2 vs. ALK3.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 13:02:10 ]
NVP-BGJ398(BGJ-398) is a novel selective, pan-specific FGFR inhibitor with IC50 of 0.9, 1.4, and 1 nM for FGFR1, FGFR2, and FGFR3, respectively; >40-fold selective for FGFR versus FGFR4 and VEGFR2, and little activity to Abl, Fyn, Kit, Lck, Lyn.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 12:59:04 ]
Dorsomorphin(Compound C; BML-275) has been shown to act as a potent and selective inhibitor of AMPK (AMP-activated protein kinase; Ki = 109 nM), induced by AICAR and metformin; also inhibits the bone morphogenetic protein type 1 receptors ACTR-I (ALK2), B
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 12:52:54 ]
GSK 525762A is an inhibitor for BET (bromodomain and extra terminal domain) proteins, BRD2, BRD3 and BRD4, binds to the tandem bromodomains of BET with Kd of 50.5-61.3 nM, displaces a tetra-acetylated H4 peptide prebound to tandem bromodomains of BET with IC50 of 32.5-42.5 nM in
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 12:48:50 ]
2-Deoxy-L-ribose CAS 18546-37-7 MF C5H10O4 MW 134.13 mp 69-72°C alpha 57 o (c=0.9 H2O after 24h) storage temp. 2-8°C Chemical Properties white to light beige crystalline powder Purity 99% Usage API Package 1KG foil bag; 25Kg drum Price us$2833
Hubei YuanCheng GongChuang Technology Co.Ltd [2015-06-03 11:56:26 ]
