AHAS inhibitor is a novel acetohydroxyacid synthase(AHAS) inhibitor, a promising drug target against Mycobacterium tuberculosis (MTB).
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 13:11:21 ]
PF-543 is a novel cell-permeant inhibitor of SphK1 with a Ki of 3.6 nM, PF-543 is sphingosine-competitive and is more than 100-fold selective for SphK1 over the SphK2 isoform.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 13:08:40 ]
ML347(DN193719) is a highly selective ALK1/ALK2 inhibitor with IC50s of 46/32 nM; shows >300-fold selectivity for ALK2 vs. ALK3.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 13:02:10 ]
NVP-BGJ398(BGJ-398) is a novel selective, pan-specific FGFR inhibitor with IC50 of 0.9, 1.4, and 1 nM for FGFR1, FGFR2, and FGFR3, respectively; >40-fold selective for FGFR versus FGFR4 and VEGFR2, and little activity to Abl, Fyn, Kit, Lck, Lyn.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 12:59:04 ]
Dorsomorphin(Compound C; BML-275) has been shown to act as a potent and selective inhibitor of AMPK (AMP-activated protein kinase; Ki = 109 nM), induced by AICAR and metformin; also inhibits the bone morphogenetic protein type 1 receptors ACTR-I (ALK2), B
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 12:52:54 ]
GSK 525762A is an inhibitor for BET (bromodomain and extra terminal domain) proteins, BRD2, BRD3 and BRD4, binds to the tandem bromodomains of BET with Kd of 50.5-61.3 nM, displaces a tetra-acetylated H4 peptide prebound to tandem bromodomains of BET with IC50 of 32.5-42.5 nM in
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 12:48:50 ]
2-Deoxy-L-ribose CAS 18546-37-7 MF C5H10O4 MW 134.13 mp 69-72°C alpha 57 o (c=0.9 H2O after 24h) storage temp. 2-8°C Chemical Properties white to light beige crystalline powder Purity 99% Usage API Package 1KG foil bag; 25Kg drum Price us$2833
Hubei YuanCheng GongChuang Technology Co.Ltd [2015-06-03 11:56:26 ]
2-Hydroxymethyl-3-methyl-4-(3-methoxy propanoxyl)pyridine CAS 118175-10-3 MF C11H17NO3 MW 211.26 Chemical Properties Colorless liquid Purity 99% Usage API Package 1KG foil bag; 25Kg drum Price us$316.6
Hubei YuanCheng GongChuang Technology Co.Ltd [2015-06-03 11:55:47 ]
Hydroxypropyl-beta-cyclodextrin Name Hydroxypropyl-beta-cyclodextrin Synonym beta-Cyclodextrin 2-hydroxypropyl ethers; HPBCD; HPCD; 2-hydroxypropyl-beta-cyclodextrin; (2-hydroxypropyl)-beta-cyclodextrin; HYDROXYPROPYL-β-CYCLODEXTRIN; beta-Cyclodextrin, 2-hydroxypropyl ether CAS
Hubei YuanCheng GongChuang Technology Co.Ltd [2015-06-03 11:52:39 ]
2-Methylpiperazine Name 2-Methylpiperazine Synonym (+/-)-2-Methylpiperazine; (2R)-2-methylpiperazinediium; (2R)-2-methylpiperazine; tert-butyl 2-methylpiperazine-1-carboxylate CAS 109-07-9 EINECS 203-644-2 Assay 99% M F C10H20N2O2 M W 200.278 MP 61-66℃ BP 268.74°C at 760 mmHg
Hubei YuanCheng GongChuang Technology Co.Ltd [2015-06-03 11:46:14 ]
4,6-Dichloro-2-methylpyrimidine CAS 1780-26-3 MF C5H4Cl2N2 MW 163 mp 41.5-45.5 °C(lit.) Fp 208 °F Chemical Properties White to off-white solid Purity 99% Usage API Package 1KG foil bag; 25Kg drum Price us$166.6
Hubei YuanCheng GongChuang Technology Co.Ltd [2015-06-03 11:45:20 ]
2-Cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-methanol Name 2-Cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-methanol Synonym 2-cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-methanol;2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinemethanol;PT-1;N-2 2-CYCLOPROPYL-4-(4-FLUOROPHENYL) -QUINOLYL-3-M
Hubei YuanCheng GongChuang Technology Co.Ltd [2015-06-03 11:42:24 ]
Ispinesib is a potent, allosteric, reversible, and specific inhibitor of KSP, which changes the binding property of KSP to microtubules and disturbs its movement by inhibiting ADP release without altering the release of the KSP-ADP complex from the microtubule. Ispinesib shows po
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 11:40:58 ]
CX-5461 is an inhibitor of rRNA synthesis, selectively inhibits Pol I-driven transcription of rRNA with IC50 of 142 nM, has no effect on Pol II, and possesses 250- to 300-fold selectivity for inhibition of rRNA transcription versus DNA replication and protein translation.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 11:34:13 ]
2-Chloroethanesulfonic acid, sodium salt monohydrate Name 2-Chloroethanesulfonic acid, sodium salt monohydrate Synonym 2-chloro-ethanesulfonicacisodiumsalt;2-CHLOROETHANESULFONIC ACID SODIUM SALT;CHLOROETHANESULFONIC ACID, NA;SODIUM 2-CHLOROETHANESULFONATE;SODIUM 2-CHLOROETHANESU
Hubei YuanCheng GongChuang Technology Co.Ltd [2015-06-03 11:34:12 ]
MLN9708 immediately hydrolyzed to MLN2238, which is an N-capped dipeptidyl leucine boronic acid and preferentially bound to and inhibited the 20S proteasome with an IC50 value of 3.4 nM (Ki = 0.93 nM).
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 11:30:36 ]
SBE13 Hcl is a potent and selective PLK1 with IC50 of 0.2 nM; no inhibition om Aurora A kinase, Plk2 and Plk3. We offer a substantial discount on orders of 5g or more.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 11:21:21 ]
Isopropyl 2-(3-nitrobenzylidene)acetoacetate CAS 39562-25-9 MF C14H15NO5 MW 277.27 Purity 99% Usage API Package 1KG foil bag; 25Kg drum Price us$333.3
Hubei YuanCheng GongChuang Technology Co.Ltd [2015-06-03 11:17:23 ]
2-(2-(3-(2-(7-Chloro-2-quinolinyl)-ethenylphenyl)-3-hydroxypropyl)phenyl)-2-propanol Name 2-(2-(3-(2-(7-Chloro-2-quinolinyl)-ethenylphenyl)-3-hydroxypropyl)phenyl)-2-propanol Synonym (s)-1-(3-(2-(7-chloro-2-quinolinyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)-phenyl)propanol
Hubei YuanCheng GongChuang Technology Co.Ltd [2015-06-03 11:15:16 ]
SU 6656 is a selective inhibitor of Src kinases, Including Src, Yes, Lyn, and Fyn (IC50 = 280, 20, 130, 170 nM, respectively). By comparing PDGF-stimulated tyrosine phosphorylation events in untreated and SU6656-treated cells, we found that some substrates (for example, c-Cbl, an
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 11:08:56 ]
