Broad Spectrum Matrix Metalloproteinase (MMP) Inhibitors

GM 6001
Ilomasta (GM 6001, GalardinTM, N-[(2R)-2-(hydroxamidocarbonylmethyl)
-4-methylpentanoyl]-L-tryptophan methylamide) Board Spectruminhibitor of matrix metalloproteases (MMPs) with Kis in nM range. Widely used to
inhibit MMPs in vitro experiments and in animal models.
Reference:
Inhibits anthrax lethal factor with ki= 2.1 uM. B.E. Turk et al, Nature
Structural and Molecular Biology 11(1) January 2004, 60-65.