Water For Injection (WFI) Generation System

FOB Price: USD $20,000.00 / Piece
Place Of Origin: china

Minimum Order: 1

Packaging: N/A

Delivery: 45days

Biocell water for injection generation system adopts an advanced three-stage separation WFI generation process of steam and water, and the quality of produced water meets the standards of Chinese, American, and European Pharmacopoeia, GMP, FDA, and other certification requirements; Humanized design, modular installation, small floor area, stable operation, one button start, simple operation and maintenance, high efficiency, and energy saving.

DIFFERENT TYPES OF WFI GENERATION SYSTEM

WHAT IS THE WFI GENERATION SYSTEM WORKING PRINCIPLE?

The WFI system in pharmaceutical industry has low investment cost, low operation, and energy consumption, and can operate continuously and dynamically. Under the condition of low-temperature storage and turbulence, water for injection machine can effectively control the microbial breeding risk of the whole system and can realize large-scale water supply.

WHAT IS WATER FOR INJECTION (WFI)？

Water for injection equipment (WFI) is a high-purity water used in the pharmaceutical industry for the preparation of injectable medications and medical devices. WFI system must meet strict quality standards to ensure that it is free from microbial and chemical contaminants that could harm patients.

What Is WFI Generator Used For

The water for injection plant (WFI) system is used as a diluent or solvent for drugs that are administered by injection, including intravenous, intramuscular, and subcutaneous injections. It is also used as a component in the preparation of medical devices, such as wound dressings and contact lenses.

The high purity of WFI is critical to ensure the safety and efficacy of the medications and devices prepared with it. Even trace amounts of contaminants can cause adverse reactions in patients, such as infections or allergic reactions. Therefore, water for injection systems is subject to strict quality standards and is regularly tested to ensure that it meets the required specifications.

WFI Generation Process

The generation of water for injection (WFI) system in the pharmaceutical industry typically involves a multi-step process to remove impurities and contaminants from the feed water. The WFI generation process may include the following steps:

Pretreatment: The first step is to remove large particles and suspended solids from the feed water. This may be accomplished by using filters, such as sand or cartridge filters.

Reverse osmosis (RO): The pretreated water is then passed through a reverse osmosis membrane, which removes dissolved salts and other impurities. RO uses high pressure to force water through a semi-permeable membrane that separates the water from dissolved salts and other contaminants.

Electrodeionization (EDI): The RO permeate is then passed through an electrodeionization (EDI) module, which uses a combination of ion exchange and electrochemical processes to remove the remaining ions from the water.

Distillation: In some cases, WFI is generated by distilled water. This involves heating the feed water to generate steam, which is then condensed to produce high-purity water.

Ultrafiltration: Ultrafiltration is a process that can be used in combination with the other steps to remove endotoxins and other small particles from the water.

What Is Water for Injection (WFI)？

WFI By Distillation

At present, water for injection system (WFI) is mainly obtained by the following thermal distillation methods:

Multiple Effect Distillation Units

Single Effect Distillation Units

Single-effect or multi-effect thermal distillation is the most popular production method of water for injection (WFI) equipment. The main advantages of this method are a simple design, and no moving parts used in the WFI water generation process, so it has reliability. Since the process is carried out at high temperatures, the method has full confidence in the microbial purity of the water obtained.

water for injection system

SECOND

Cold WFI by Membrane Methods

When using the whole membrane method to prepare cold water for injection, special attention should be paid to the design of regular sanitary treatment of the system. Cold process is always more susceptible to microbial contamination than traditional hot distillation. The cold WFI power generation equipment shall be cleaned regularly, preferably by thermal disinfection.

For more information about water system pharmaceutical industry, please feel free to contact us!

Country: China (Mainland)
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Water For Injection (WFI) Generation System

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