Lidocaine Powder CAS 137-58-6 Local Anesthetics China Factory Price
Product Quick Detail
- FOB Price
- USD $14.00 / Piece
- Place Of Origin
- china
- Minimum Order
- 1
- Packaging
- 25kg per drum
- Delivery
- 15 Days
Specifications
Use of Lidocaine
Lidocaine, an amide local anesthetic, has anti-inflammatory properties in vitro and in vivo, possibly due to an attenuation of pro-inflammatory cytokines, intracellular adhesion molecule-1 (ICAM-1), and reduction of neutrophils influx.Target: Lidocaine is a common local anesthetic and antiarrhythmic drug. Lidocaine is used topically to relieve itching, burning and pain from skin inflammations, injected as a dental anesthetic or as a local anesthetic for minor surgery. Lidocaine, the first amino amide–type local anesthetic, was first synthesized under the name xylocaine by Swedish chemist Nils Lofgren in 1943. His colleague Bengt Lundqvist performed the first injection anesthesia experiments on himself.Lidocaine is approximately 95% metabolized (dealkylated) in the liver by CYP3A4 to the pharmacologically-active metabolites monoethylglycinexylidide (MEGX) and then subsequently to the inactive glycine xylidide. MEGX has a longer half life than lidocaine but also is a less potent sodium channel blocker. The elimination half-life of lidocaine is approximately 90–120 minutes in most patients. This may be prolonged in patients with hepatic impairment (average 343 minutes) or congestive heart failure (average 136 minutes).
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cas number: 137-58-6 Boiling Point: 372.7±52.0 °C at 760 mmHg Melting Point: 66-69°C Molecular Formula: C14H22N2O Molecular Weight: 234.337 Exact Mass: 234.173218 PSA: 32.34000 LogP: 3.63 Index of Refraction: 1.512 Water Solubility: / packing: 25kg fiber can shippment: by ...
