Vandetanib

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[(1-methylpiperidin-4-yl)methoxy]quinazoline;N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-[(1-methyl-4-piperidinyl)methoxy]-4-quinazolinamine;Zactima;ZD 6474;7-((4-aminocyclohexyl)methoxy)-N-(4-bromo-2-fluorophenyl)-6-methoxyquinazolin-4-amine
CAS: 443913-73-3
MF: C22H24BrFN4O2
MW: 475.35
Product Categories: Aromatics Compounds;Aromatics;Heterocycles;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Pharmaceutical intermediate;ZD6474
mp 240-2430C
density 1.406
storage temp. -20deg;C Freezer
Chemical Properties Yellow Solid
Usage Vandetanib (Zactima, ZD6474) is a potent inhibitor of VEGFR2 with IC50 of 40 nM.
Usage Vandetanib (ZD6474) is a potent inhibitor of VEGFR2 with IC50 of 40 nM
Usage Vandetanib is a once-daily oral inhibitor of vascular endothelial growth factor receptor-2 and epidermal growth factor receptor kinase activity. The activity of Vandetanib plus Docetaxel was assessed in patients with previously treated non-small-cell lung cancer (NSCLC).

Vandetanib Introduction:

Vandetanib (INN, trade name Caprelsa) is an anti-cancer drug that is used for the treatment of certain tumours of the thyroid gland.It acts as a kinase inhibitor of a number of cell receptors, mainly the vascular endothelial growth factor receptor (VEGFR), the epidermal growth factor receptor(EGFR), and the RET-tyrosine kinase.The drug was developed by AstraZene .

Vandetanib Function:

An anticancer drug that is used for the treatment of certain tumours of the thyroid gland.It acts as a kinase inhibitor of a number of cell receptors, mainly the vascular endothelial growth factor receptor (VEGFR), the epidermal growth factor receptor (EGFR), and the RET-tyrosine kinase.Vandetanib is an orally active small molecule tyrosine kinase inhibitor (TKI) with activity against several pathways implicated in malignancy including the vascular endothelial growth factor receptor pathway, the epidermal growth factor receptor pathway, the platelet derived growth factor receptor pathway, and REarranged during Transfection pathway.

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Safe 99% API Intermediates 443913-73-3 Vandetanib for Cancer Treatment
Safe 99% API Intermediates 443913-73-3 Vandetanib for Cancer Treatment

Product Name: Vandetanib Synonyms: VANDETANIB;4-Quinazolinamine, N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methyl-4-piperidinyl)methoxy]-;Vandetanib for research;4-(4-Bromo-2-fluoroanilino)-6-methoxy- ...

Jinan Jia Ge Biological Technology Co.,Ltd

Vandetanib
Vandetanib

Product Name: Vandetanib Synonyms: VANDETANIB;4-Quinazolinamine, N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methyl-4-piperidinyl)methoxy]-;Vandetanib for research;4-(4-Bromo-2-fluoroanilino)-6-methoxy- ...

Yuancheng Group

Vandetanib
Vandetanib

Product Name: Vandetanib Synonyms: VANDETANIB;4-Quinazolinamine, N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methyl-4-piperidinyl)methoxy]-;Vandetanib for research;4-(4-Bromo-2-fluoroanilino)-6-methoxy- ...

hubei fangda group

Vandetanib        service01@chembj.com
Vandetanib service01@chembj.com

Vandetanib CAS:443913-73-3 MF:C22H24BrFN4O2 MW:475.35 Type:Anesthetic Agents, Anti-Allergic Agents, Antibiotic and Antimicrobial Agents, Grade Standard:Cosmetic Grade, Feed Grade, Food Grade, Medicine Grade, Tech Grade Place of Origin:China (Mainland) Density:1.406 g/cm3 ...

Zhuhai Shuangbojie Pharmaceutical Technology Co.,Ltd

Vandetanib  CAS: 443913-73-3
Vandetanib CAS: 443913-73-3

Alias: 4-Quinazolinamine, N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methyl-4-piperidinyl)methoxy]-;Vandetanib for research;4-(4-Bromo-2-fluoroanilino)-6-methoxy- 7-[(1-methylpiperidin-4-yl)methoxy]quinazoline CAS: 443913-73-3 M.F.: C22H24BrFN4O2 M.W.: 475.35 Choose our ...

株洲远成合中科技发展有限公司(株洲)

Vandetanib  CAS: 443913-73-3
Vandetanib CAS: 443913-73-3

Vandetanib http://www.steroidsgym.com/ Skype: yczht123456 ycgl08@yccreate.com CAS: 443913-73-3 M.F.: C22H24BrFN4O2 M.P.: 240-243°C http://www.steroidsgym.com/ Skype: yczht123456 ycgl08@yccreate.com ...

Zhuzhou Yuancheng Hezhong

Vandetanib  CAS: 443913-73-3
Vandetanib CAS: 443913-73-3

Vandetanib http://www.steroidsgym.com/ Skype: yczht123456 ycgl08@yccreate.com Alias: 4-Quinazolinamine CAS: 443913-73-3 M.F.: C22H24BrFN4O2 M.W.: 475.35 M.P.: 240-243°C http://www.steroidsgym.com/ Skype: yczht123456 ycgl08@yccreate.com ...

Zhuzhou Yuancheng Hezhong Technology Development Co., Ltd.

Vandetanib  CAS: 443913-73-3
Vandetanib CAS: 443913-73-3

Vandetanib http://www.steroidsgym.com/ Skype: yczht123456 ycgl08@yccreate.com CAS: 443913-73-3 M.F.: C22H24BrFN4O2 M.W.: 475.35 M.P.: 240-243°C http://www.steroidsgym.com/ Skype: yczht123456 ycgl08@yccreate.com ...

Zhuzhou Yuancheng Hezhong

Vandetanib  CAS: 443913-73-3
Vandetanib CAS: 443913-73-3

Vandetanib http://www.steroidsgym.com/ Skype: yczht123456 ycgl08@yccreate.com CAS: 443913-73-3 M.F.: C22H24BrFN4O2 M.W.: 475.35 M.P.: 240-243°C http://www.steroidsgym.com/ Skype: yczht123456 ycgl08@yccreate.com ...

Zhuzhou Yuancheng Hezhong Technology Development Co., Ltd.