Synonyms:ABL2 (38-end), active, His tagged human;FLJ41441;ANTI-ABL2 antibody produced in mouse;FLJ22224;FLJ31718;Abelson murine leukemia viral oncogene homolog 2;Abelson tyrosine-protein kinase
Mol File: 74-79-3.mol
Product Categories:pharmacetical;Amino Acids
1. Improves Heart Health
Research shows that l-arginine is beneficial for lowering inflammation and improving the health of the blood vessels and cardiovascular system, which is why it’s one of the most popular supplements
recommended by cardiologists. For people with high risk factors for coronary heart disease, L-arginine supplements can be an effective measure for preventing a heart attack or stroke.
Some of the ways that L-arginine improves cardiovascular health include: preventing high blood pressure, improving blood flow in people with clogged arteries (coronary artery disease), lowering
high cholesterol, helping to relieve congestive heart failure, improving stamina, and reducing symptoms associated with cut-off blood flow from the heart to the limbs (called claudication).
It’s also commonly used for treating chest pains (angina pectoris) because of the effects of nitric oxide preventing blood clots (thrombosis) that cut off blood supply. Two to three grams a day of
L-arginine supplementation has been shown to resolve nitrate intolerance in most people with angina according to some studies. And finally, L-arginine is capable of safely improving exercise
performance in people with low stamina, circulation problems and a history of heart disease.
2. Lowers Inflammation and Fights the Effects of Aging
Beyond heart health, one of the primary benefits of L-arginine is fighting disease-causing inflammation and raising immune function. L-arginine has been found to have substantial free
radical-scavenging abilities due to its effects on the enzyme called superoxide dismutase (SOD) as well as other antioxidant mechanisms. It’s commonly used in combination with antioxidants like
vitamin C and omega-3 fish oil supplements, helping to slow the aging process and preventing many chronic diseases.
L-arginine also positively affects both central nervous system and immune system functions since in the brain NO acts as a neurotransmitter and protective agent against outside threats. Helpful for
detoxifying the body, L-arginine can even lower the presence of ammonia within the blood, which is why it’s sometimes used to treat people with metabolic problems and damage to the urethra where
ammonia is excreted from the body. Ammonia (ammonium hydroxide) is a product of the body breaking down proteins, and one cause of necrosis of tissues that can lead to cellular destruction and
3. Boosts Exercise Performance
L-arginine is known to effectively improve blood flow, which means it helps bring nutrients and oxygen to muscle and joint tissues. This means with L-arginine’s help you can enjoy more of the many
benefits of exercise but with less pain. It’s even used in some cases for increasing heat and circulation to damaged joints or cold hands and feet, especially in people with complications from
other health conditions like poor blood flow, arthritis or diabetes. For example, in people suffering from painful intermittent claudication (narrowing of blood vessels in the legs and feet caused
by fatty deposits), L-arginine supplementation has been shown to improve walking distance and lower muscle aches and pains.
Also importantly, L-arginine is used by the body to increase production of human growth hormone, prolactin and several amino acids - including creatine, L-proline and L-glutamate. It even improves
sensitivity to insulin, similarly to how exercise does, by allowing more glucose to enter cells. L-arginine’s roles in metabolic health are important for building strong muscle tissue, fighting
inflammation causing bone and joint pain, repairing injuries, and for general nervous system functions.
Some studies have found that growth hormone levels can significantly increase with L-arginine supplementation in doses between five to nine grams a day. In most cases, L-arginine increases resting
growth hormone levels at least 100 percent (in comparison, regular exercise can increase growth hormone levels by 300 percent to 500 percent). Even more powerful is the combination of L-arginine
plus exercise. There’s also evidence that L-arginine supplementation increases plasma insulin and helps builds stronger muscles even when you’re resting due to its effects on the body’s
capillaries. These hormonal changes affect your metabolism in a positive way by helping to repair, build and maintain the youthful foundation of the skeletal-muscle system.
4. Improves Immunity, Helps Prevent Infections and Speeds Up Healing
Low-circulating L-arginine has been found in some patients suffering from illnesses, trauma and cancer. It’s believed that certain immune system suppressor cells (called MSCs) might cause arginine
deficiency or low levels circulating within the blood. This is problematic because the immune system’s protective lymphocytes and T-cells depend on arginine for defending the body.
L-arginine is used with omega-3 fish oils and other supplements for reducing risk for infections (especially respiratory infections or problems with the lungs); improving wound healing; and
shortening recovery time following cancer, illness or surgery. It’s sometimes added to topical ointments used to treat wounds for several reasons: It helps keep blood flowing more freely, can fight
pain and swelling, forms L-proline, which is important for collagen synthesis within the skin, and increases antioxidant activity.
It’s also used to improve protein function in helping to heal burns and might even help fight cavities and tooth decay! And although more research is still needed, because L-arginine has
immune-enhancing effects, it’s commonly given to people undergoing chemotherapy or healing from surgeries, viruses and infections (including HIV).
5. Helps Treat Erectile Dysfunction and Infertility
A number of studies have shown that L-arginine is involved in the process of proper cell replication in addition to enhancing blood circulation, so it can help improve both sperm production and
motility. Men who deal with cardiovascular problems tied to low levels of NO in the blood are more likely to suffer from erectile dysfunction and fertility issues, since an erection requires the
relaxation of smooth muscles triggered by nitric oxide. While not effective for every man, a significant percentage of male infertility cases (up to 92 percent, according to some studies) can be
treated with L-arginine supplements combined with other dilators, antioxidants or anti-inflammatories.
Some research suggests that high stress levels can lower the presence of L-arginine in the sperm production pathway, so overly stressed men can especially benefit from supplementing. A combination
of L-arginine, L-glutamate and yohimbine hydrochloride are commonly used to treat ED and seem to work better than L-arginine alone. In fact, many of the most commonly prescribed medications for ED
work similarly to L-arginine by increasing nitric oxide production.
Even women can experience better reproductive help from L-arginine - doctors sometimes prescribe topical creams that contain this amino acid for helping heal sexual problems and naturally treat
infertility in both sexes since it improves circulation to genital tissue. Additionally, there’s some research that suggests treatment with N-acetyl cysteine (NAC) and L-arginine together can help
balance hormones naturally and restore normal sexual function in women with polycystic ovary syndrome and estrogen imbalances. Other studies suggest that L-arginine used with herbs like
chasteberry, green tea extract and antioxidant supplements improve pregnancy rates in women struggling to conceive.
The dosage of L-arginine depends a lot on the condition it’s being used to treat; for example, with help treating heart conditions or erectile dysfunction, three to six grams daily (divided into
two doses) might be taken, while for enhancing exercise performance, doses up to nine grams a day are not uncommon. For generally healthy adults who are looking to prevent inflammation and benefit
from better circulation, about one gram daily (1,000 milligrams) is usually the recommended dose.