Vapreotide Acetate

Minimum Order: 1

Packaging: N/A

Delivery: 15 Days

Product Name Vapreotide Acetate

Sequence D-Phe-[Cys-Tyr-D-Trp-Lys-Val-Cys]-Trp-NH2

Cas No. 103222-11-3

Molecular Formula C57H70N12O9S2

Molecular Weight 1131.40

Purity (HPLC) 98.0%

Appearance? White powder

Single Impurity(HPLC)? 1.0%

Amino Acid Composition? 10% of theoretical

Peptide Content(N%) 80%(by %N)

2. Description:

Variceal bleeding is a life-threatening complication of portal hypertension. The recommended treatment includes the early administration of a vasoactive drug. Vapreotide is a somatostatin analogue with a different receptor affinity to octreotide. It decreases portal pressure and blood flow of collateral circulation in rats with cirrhosis. The pivotal study of early administration of vapreotide in patients with cirrhosis and variceal bleeding has shown a significant improvement in bleeding control and, in the subset of patients with significant bleeding, a significant reduction in mortality. In addition, a meta-analysis of four randomized studies has shown a significant improvement in bleeding control. Vapreotide administrated via the intravenous route is simple to use, with practically no contraindications and few, usually minor, side effects.

3. Application:

The immediate release formulation of Sanvar, a somatostatin analogue, is used in the treatment of acute esophageal variceal bleeding (EVB).

Sanvar is used prior to endoscopic intervention to control haemorrhage and prevent re-bleeding during the critical five days following the onset of bleeding. EVB is a life threatening condition and the mortality rate is high (about 15% to 25%) in the first six weeks following the haemorrhage. EVB is the cause of about 70% of gastro-intestinal bleeding in patients suffering from liver cirrhosis.

Sanvar (vapreotide acetate) is a synthetic octapeptide analogue of the naturally-occurring somatostatin hormone. It has similar pharmacological properties to native somatostatin, but exhibits a longer duration of action. It is the only somatostatin analogue to have demonstrated statistically significant benefits in the early treatment of EVB in association with endoscopic therapy, in a placebo-controlled clinical study (Calè S et al. New England Journal of Medicine, 2001). Control of bleeding with survival at five days was achieved more often with Sanvar (p=0.021) than with placebo. Additional Phase III trials have been completed in Europe in this indication. Sanvar can be stored at room temperature, an advantage over other products requiring refrigeration, allowing immediate administration, a key benefit in a life-threatening situation. The product has been granted orphan drug status in the U. S., where there is currently no FDA approved treatment for this indication.

Country: China (Mainland)
Business Type: Trading Company,Manufacturer
Market:Americas,European Union,Emerging Markets
Founded Year:2009
Address:No. 496 Zhongshan Road, Wuchang, Wuhan, Hubei, CHINA
Contact:Alan Ma

vapreotide acetate

*Your name:	Enter name here eg:Ralph zhang
*Your Email:	Enter email here
*To:	Wuhan Yuancheng Phamacy Co., Ltd
*Subject:
*Message:
	Enter between 20 to 3,000 characters. English only. Characters : 0 / 3000
*Enter the secure code shown below	Reload Image

		We do inquire for you , please wait ...

Nesiritide Acetate (BNP-32)

Ziconotide Acetate

Vapreotide Acetate

Thymosin β4 Acetate

Thymosin α1 Acetate

Acetic Acid

Concentrated acetic acid, also known as ethanoic acid or methane carboxylic acid, is the active ingredient in vinegar, effective in multiple cooking and cleaning applications. It is used as a buffer in chemical reactions and solutions including protic solvents. Properties: ...

ramluca478@gmail.com

SILICONE SEALANT-ACETIC

7CF silicone sealant-acetic is a kind of acid glue with wide application and strong durability, which is used for sealing of glass and general building materials, and has excellent bonding performance to glass and most building materials.Trust in our expertise as a leading ...

Shenzhen Sunrise New Energy Co.,Ltd.

Trenbolone Acetate (Finaplix H/Revalor-H)

Email: Amber@aasrawshop.com Web:https://www.steroidraw.com/ Whatsapp：+63 9054356298 ...

MANUFACTURER

Clostebol acetate (Turinabol)

Email: Amber@aasrawshop.com Web:https://www.steroidraw.com/ Whatsapp：+63 9054356298 ...

MANUFACTURER

Testosterone Acetate

Email: Amber@aasrawshop.com Web:https://www.steroidraw.com/ Whatsapp：+63 9054356298 ...

MANUFACTURER

CAS 121062-08-6 Melanotan II acetate salt

14030-76-3 Etazene 14176-50-2 Tiletamine hydrochloride 14680-51-4 Metonitazene 71368-80-4 Bromazolam 109555-87-5 3-(1-Naphthoyl)indole 119276-01-6 Protonitazene (hydrochloride) 2647-50-9 Flubromazepam 2894-61-3 Bromonordiazepam 28981-97-7 Alprazolam 2732926-24-6 N-desethyl ...

Hebei Fangpai New Material Technology

CAS 121062-08-6 Melanotan II acetate salt

We have our own factory We can provide good products at reasonable prices. We can send it free of charge, but you have to pay the freight. People who need to study chemicals for medical and laboratory technical purposes look forward to your contact. ...

Hebei Fangpai

CAS 83150-76-9 Octreotide acetate

whatsapp/Tel:+8617325200957 Telegram:Shankles Zhang +8617325200957 email:huamy04@wuhanhuamy.com skype:+8617325200957 Our factory can provide these products. HOT sale product 5CL 5F ADBB SGT JWH 2fdck 3mmc 3cmc Eutylone NEP CAS 40064-34-4 4,4-Piperidinediol hydrochloride CAS ...

武汉桦美新材料有限公司