Irinotecan Hydrochloride Trihydrate
Product Quick Detail
- FOB Price
- USD $160.00 / Piece
- Place Of Origin
- China
- Minimum Order
- 100
- Packaging
- Aluminum Foil Bags or Fiber Drum.
- Delivery
- 15 Days
Specifications
Fine Chemical Irinotecan Hydrochloride triHydrate
(CAS: 136572-09-3)
=====================================
Chemical Information:
Quick Details:
Product Name: Irinotecan Hydrochloride triHydrate
Other Names: Camptosar; Campto; CPT-11
Model No.: REB-533
CAS No.: 136572-09-3
Molecular Formula: C33H38N4O6?HCl?3H2O
Molecular Weight: 677.1
Appearance: White or Nearly White Crystalline Powder
Purity: â¥99%
Product Specifications: Pharmaceutical Grade
Standard: Qualified
MOQ(Minimum Order Quantity): 100g
=====================================
Product Description:
Irinotecan hydrochloride trihydrate, Irinotecan (CPT 11), a compound within the camptothecin family, is an inhibitor of Topo I (topoisomerase I) involved in cellular DNA replication and transcription. As a Topo I inhibitor, Irinotecan inhibits the religation step of the enzyme's normal action, inducing single stranded DNA breaks. These single stranded breaks are then converted to double-stranded breaks within the course of DNA replication which is reported to induce apoptosis or repair mechanisms as a result. Irinotecan is activated by esterases to produce the activated metabolite, SN 38 (sc-203697) and has been reported to be associated with cleavage of poly (ADP-ribose) polymerase (PARP) in colon carcinoma cells. Irinotecan's active metabolite SN 38 is additionally noted to activate p53 in the Huh7 cell line.
=====================================
Applications/Usage:
The product is used as chemical reagents, organic intermediates, fine chemicals, pharmaceutical research and development.
Irinotecan hydrochloride trihydrate is a kind of natural camptothecin derivatives with was been chemcial structural modified. It is a new anti-cancer drugs of curative effect and less side effects. Mainly used for the treatment of digestive system neoplasm, such as stomach cancer, colon cancer, rectal cancer, lung cancer. Also be used to treat leukemia, hydatidiform mole and chorionic carcinoma.
ABOUT DELIVERY: 
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OUR COMMITMENT: 
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CONTACT US:
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If you want to source ...
#1 Pharmaceutical raw material,
#2 Oncology drug APIs,
#3 Antibiotics or fine chemicals,
We are a reliable manufacturer and supplier in China.
NEWBIO would like to ...
#1 We foucus on the high purity and high quality;
#2 We provide the raw materials at a good price;
#3 We have the best service and we are always there for you.
Please contact us for more infomation!!!
(CAS: 136572-09-3)
=====================================
Chemical Information:
Quick Details:
| Product Name | Irinotecan Hydrochloride triHydrate |
| CAS No. | 136572-09-3 |
| Molecular Formula | C33H38N4O6?HCl?3H2O |
| Molecular Weight | 677.1 |
Product Name: Irinotecan Hydrochloride triHydrate
Other Names: Camptosar; Campto; CPT-11
Model No.: REB-533
CAS No.: 136572-09-3
Molecular Formula: C33H38N4O6?HCl?3H2O
Molecular Weight: 677.1
Appearance: White or Nearly White Crystalline Powder
Purity: â¥99%
Product Specifications: Pharmaceutical Grade
Standard: Qualified
MOQ(Minimum Order Quantity): 100g
=====================================
Product Description:
Irinotecan hydrochloride trihydrate, Irinotecan (CPT 11), a compound within the camptothecin family, is an inhibitor of Topo I (topoisomerase I) involved in cellular DNA replication and transcription. As a Topo I inhibitor, Irinotecan inhibits the religation step of the enzyme's normal action, inducing single stranded DNA breaks. These single stranded breaks are then converted to double-stranded breaks within the course of DNA replication which is reported to induce apoptosis or repair mechanisms as a result. Irinotecan is activated by esterases to produce the activated metabolite, SN 38 (sc-203697) and has been reported to be associated with cleavage of poly (ADP-ribose) polymerase (PARP) in colon carcinoma cells. Irinotecan's active metabolite SN 38 is additionally noted to activate p53 in the Huh7 cell line.
=====================================
Applications/Usage:
The product is used as chemical reagents, organic intermediates, fine chemicals, pharmaceutical research and development.
Irinotecan hydrochloride trihydrate is a kind of natural camptothecin derivatives with was been chemcial structural modified. It is a new anti-cancer drugs of curative effect and less side effects. Mainly used for the treatment of digestive system neoplasm, such as stomach cancer, colon cancer, rectal cancer, lung cancer. Also be used to treat leukemia, hydatidiform mole and chorionic carcinoma.
FEATURED PRODUCT:
| Wuhan Newbio Pharm-tech Co., Ltd. | |||||
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| 5 | 850140-72-6 | Afatinib | 29 | 184475-55-6 | Gefitinib Hydrochloride |
| 6 | 330784-47-9 | Avanafil | 30 | 136572-09-3 | Irinotecan Hydrochloride TriHydrate |
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| 24 | 133040-01-4 | Eprosartan | 47 | 170791-09-0 | Trityl Candesartan Cilexetil |
ABOUT DELIVERY:
#1 Products can be sent out within 24 hours after payment.
#2 Secure and discreet shipment.
#3 Various methods for your choice, like DHL/FedEx/SF-express.
OUR COMMITMENT:
#1 We are manufacturer with own factory and we sale this product at a best quality and low price.
#2 All product listed is available in stock, please contact the sale for more details.
#3 We have QA&QC department to guarantees the quality, product pass rate can reach 100%.
#2 All product listed is available in stock, please contact the sale for more details.
#3 We have QA&QC department to guarantees the quality, product pass rate can reach 100%.
CONTACT US:
| Telephone | +86-027-87002705 |
| Mobile | +86-13277093700 |
| newbiopharmtech | |
| FaceBook Page | https://www.facebook.com/newbiopharma/ |
| Facebook Group | https://www.facebook.com/groups/1739616069613416/ |
| Website | http://www.newbiopharm.com/ |
| Online Store | http://biocar.en.made-in-china.com/ |
If you want to source ...
#1 Pharmaceutical raw material,
#2 Oncology drug APIs,
#3 Antibiotics or fine chemicals,
We are a reliable manufacturer and supplier in China.
NEWBIO would like to ...
#1 We foucus on the high purity and high quality;
#2 We provide the raw materials at a good price;
#3 We have the best service and we are always there for you.
Please contact us for more infomation!!!
- Country: China (Mainland)
- Business Type:
- Market:
- Founded Year:2015
- Address:
- Contact:Jason Edwards
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