Sitagliptin Phosphate Monohydrate

FOB Price
USD $280.00 / Piece
Place Of Origin
Hubei, China
Minimum Order
100
Packaging
Aluminum Foil Bags or Fiber Drum.
Delivery
15 Days

Fine Chemicals Sitagliptin Phosphate Hydrate
(CAS: 654671-77-9)

Chemical information
Product Name: Sitagliptin Phosphate Hydrate
Synonym: 7-[(3R)-3-Amino-1-oxo-4-(2,4,5-trifluorophenyl)Butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazinephosphatemonohydrate;Sitagliptin phosphate monohydrate;Sitagliptin phosphate for research;D06645;Januvia (tn);Sitagliptin phosphate (usan);Sitagliptin phosphate hydrate;Sitagliptin phosphate hydrate (jan)
Appearance: white crystalline
CAS No.: 654671-77-9
Molecular Formula: C16H20F6N5O6P
Molecular Weight: 523.3240802
Purity: 99%+
Packing: Foil Bag or as Required
Product Description:
Sitagliptin phosphate monohydrate is a white to off-white, crystalline, non-hygroscopic powder. It is soluble in water and N,N-dimethyl formamide; slightly soluble in methanol; very slightly soluble in ethanol, acetone, and acetonitrile; and insoluble in isopropanol and isopropyl acetate.
An anti-diabetic (antihyperglycemic) drug of the dipeptidyl peptidase-4 (DPP-4) class. Inhibition of the enzyme DPP-4 is thought to increase Glucagon-like peptide-1 (GLP-1) which inhibits glucagon release , stimulates the insulin release and lowers blood glucose.
What it is used for:
Sitagliptin phosphate monohydrate is used to lower blood sugar levels in patients with type 2 diabetes mellitus alone or in combination with certain other medicines (metformin, medicines such as rosiglitazone and pioglitazone, a sulfonylurea medicine such as glimepiride, gliclazide and glibenclamide), when diet plus exercise or the other medicine(s) do not provide adequate blood sugar level control.
COA:

Tests Specifications Results
Characters White to off-white crystalline powder Complies
Identification IR:similar to Reference Standard Complies
Appearance of solution Clear and colorless Complies
Loss on Drying ≤0.5% 0.06%
Sulphated Ash ≤0.2% 0.03%
Heavy metals ≤0.002% Complies
Related Compouds
  1. Single Impurity ≤1.0%
  2. Sum of Impurity≤2.0%
Undetected

Undetected

Assay(Anhydrous) 98.0% to 102% 100.2%

FEATURED PRODUCT:
Wuhan Newbio Pharm-tech Co., Ltd.
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