alpha:n* - Manufacturers, Suppliers & Exporters
Axitinib is a multi-target inhibitor of VEGFR1 , VEGFR2 , VEGFR3 , PDGFRβ and c-Kit with IC50 of 0.1 nM, 0.2 nM, 0.1-0.3 nM, 1.6 nM and 1.7 nM in Porcine aorta endothelial cells, respectively.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 09:57:37 ]
LY2835219 is an orally available cyclin-dependent kinase (CDK) inhibitor that targets the CDK4 (cyclin D1) and CDK6 (cyclin D3) cell cycle pathway, with potential antineoplastic activity. LY2835219 specifically inhibits CDK4 and 6, thereby inhibiting retinoblastoma (Rb) protein p
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 09:51:30 ]
Nintedanib esylate (BIBF 1120 esylate) is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β with IC50 of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/65 nM.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 09:46:36 ]
ARRY-438162 (625 nM) inhibits in vitro osteoclast differentiation with IC50 of 39 nM. ARRY-438162 (10 μM) inhibits in vitro osteoclast resorption with IC50 of 625 nM. ARRY-438162 (2 μM) weakly affects osteoblast differentiation. ARRY-438162 is a recently disclosed potent and se
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 09:37:50 ]
BKM120 is a n orally bioavailable specific oral inhibitor of the pan-class I phosphatidylinositol 3 kinase (PI3K) family of lipid kinases with potential antineoplastic activity. Buparlisib specifically inhibits class I PIK3 in the PI3K/AKT kinase (or protein kinase B) signaling p
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 09:32:15 ]
Daclatasvir (BMS-790052; EBP 883) is a first-in-class, highly-selective oral HCV NS5A inhibitor. We do not have so much in stock right now. If you are in need of them, please hurry up.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 09:28:35 ]
Cabozantinib is a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM, respectively .
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 09:18:31 ]
Cabozantinib S-malate is a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM, respectively.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 09:14:30 ]
Cediranib (AZD2171) is a highly potent VEGFR(KDR) inhibitor with IC50 of <1 nM, also inhibits Flt1/4 with IC50 of 5 nM/≤3 nM, similar activity against c-Kit and PDGFRβ, 36-, 110-fold and >1000-fold selective more for VEGFR than PDGFR-α, CSF-1R and Flt3.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-02 15:00:50 ]
Cerdulatinib (PRT-062070) is an oral active, multi-targeted tyrosine kinase inhibitor with IC50 of 12 nM/6 nM/8 nM/0.5 nM and 32 nM for JAK1/JAK2/JAK3/TYK2 and Syk , respectively. Also inhibits 19 other tested kinases with IC50 less than 200 nM
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-02 14:58:25 ]
Chenodeoxycholic Acid (CDCA), is a hydrophobic primary bile acid that activates nuclear receptors(FXR) involved in cholesterol metabolism.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-02 14:55:33 ]
Coluracetam(MKC-231) is a new choline uptake enhancer.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-02 14:52:15 ]
Crizotinib is inhibitor of the c-Met kinase and the NPM-ALK.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-02 14:47:48 ]
Eletriptan hydrobromide is a orally active, selective 5-HT1B/1D receptor agonist Eletriptan hydrobromide produces a dose-dependent reduction in carotid artery blood flow in vivo. Displays antimigraine activity.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-02 14:44:43 ]
EMD 1214063 is a potent and selective c-Met inhibitor with IC50 of 4 nM, >200-fold selective for c-Met than IRAK4, TrkA, Axl, IRAK1, and Mer
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-02 14:41:33 ]
LGX818 is an orally available mutated BRaf V600E inhibitor(IC50=0.3 nM) with potential antineoplastic activity.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-02 14:38:51 ]
EPZ-5676 is a potent and selective aminonucleoside inhibitor of DOT1L histone methyltransferase with Ki of 80 pM; demonstrating >37,000-fold selectivity against all other PMTs tested, inhibits H3K79 methylation in tumor.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-02 14:36:23 ]
Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-02 14:33:11 ]
Hot selling fashionable Sublimationblank phone caseNexus Google4 E960 Model GN-04 Material PC hard plastic phone Case + Sublimation Aluminum metal Insert/metal sheet Double Sided Adhesive Tape already stick on the back of phone case before ship out,so that will save your time to
SUBTRANSFER TECHNOLOGY CO., LIMITED [2015-06-01 10:20:03 ]
Non sparking tools aluminum bronze alloy combination plier lineman 1.non sparking lineman plier 2.aluminum bronze alloy 3.die forged processing 4.own factory 5.ISO9001 certification
HEBEI TUOKAI SAFETY TOOLS CO.,LTD [2015-06-01 09:24:29 ]
