alpha:c* - Manufacturers, Suppliers & Exporters
RKI-1447 inhibits potently ROCK1 and ROCK2 in a dose-dependent manner with IC50 values of 14.5 nM and 6.2 nM, respectively. RKI-1447 suppressed phosphorylation of the ROCK substrates MLC-2 and MYPT-1 in human cancer cells, but had no effect on the phosphorylation levels of the AK
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 13:23:13 ]
SGI-1027 is a potent and selective inhibitor of DNA methyltransferase (DNMT) with IC50 of 6, 8, 7.5 μM for DNMT1, DNMT3A, and DNMT3B, respectively.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 13:18:17 ]
UNC2250 is a phosphorylation of endogenous Mer inhibitor with an IC50 of 9.8 nM and blocked ligand-stimulated activation of a chimeric EGFR-Mer protein.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 13:15:28 ]
AHAS inhibitor is a novel acetohydroxyacid synthase(AHAS) inhibitor, a promising drug target against Mycobacterium tuberculosis (MTB).
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 13:11:21 ]
PF-543 is a novel cell-permeant inhibitor of SphK1 with a Ki of 3.6 nM, PF-543 is sphingosine-competitive and is more than 100-fold selective for SphK1 over the SphK2 isoform.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 13:08:40 ]
Alogliptin benzoate(SYR 322) is a potent, selective inhibitor of DPP-4 with IC50 of <10 nM, exhibits greater than 10,000-fold selectivity over DPP-8 and DPP-9.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 13:05:15 ]
ML347(DN193719) is a highly selective ALK1/ALK2 inhibitor with IC50s of 46/32 nM; shows >300-fold selectivity for ALK2 vs. ALK3.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 13:02:10 ]
NVP-BGJ398(BGJ-398) is a novel selective, pan-specific FGFR inhibitor with IC50 of 0.9, 1.4, and 1 nM for FGFR1, FGFR2, and FGFR3, respectively; >40-fold selective for FGFR versus FGFR4 and VEGFR2, and little activity to Abl, Fyn, Kit, Lck, Lyn.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 12:59:04 ]
Dorsomorphin(Compound C; BML-275) has been shown to act as a potent and selective inhibitor of AMPK (AMP-activated protein kinase; Ki = 109 nM), induced by AICAR and metformin; also inhibits the bone morphogenetic protein type 1 receptors ACTR-I (ALK2), B
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 12:52:54 ]
GSK 525762A is an inhibitor for BET (bromodomain and extra terminal domain) proteins, BRD2, BRD3 and BRD4, binds to the tandem bromodomains of BET with Kd of 50.5-61.3 nM, displaces a tetra-acetylated H4 peptide prebound to tandem bromodomains of BET with IC50 of 32.5-42.5 nM in
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 12:48:50 ]
methyl 6-fluoro-3,4-dihydro-2H-chromene-2-carboxylate Name methyl 6-fluoro-3,4-dihydro-2H-chromene-2-carboxylate Synonym methyl 6-fluoro-3,4-dihydro-2H-chromene-2-carboxylate;rac-6-Fluoro-3,4-dihydro-2H-1-benzopyran-2-carboxylic Acid Methyl Ester;methyl 6-fluorochroman-2-carboxyl
Hubei YuanCheng GongChuang Technology Co.Ltd [2015-06-03 11:59:28 ]
Ethyl-2-phenyl-2-cyanobutylate Name Ethyl-2-phenyl-2-cyanobutylate Synonym (R,S)-Ethylphenylcyano-aceticacidethylester ; ETHYL ETHYLPHENYLCYANOACETATE ; ethylphenylcyano-acetic acid ethyl ester ; (r,s)-2-cyano-2-phenyl-butyric acid ethyl ester ; Ethyl 2-Phenyl-2-cyanobutyl acid e
Hubei YuanCheng GongChuang Technology Co.Ltd [2015-06-03 11:57:03 ]
Hydroxypropyl-beta-cyclodextrin Name Hydroxypropyl-beta-cyclodextrin Synonym beta-Cyclodextrin 2-hydroxypropyl ethers; HPBCD; HPCD; 2-hydroxypropyl-beta-cyclodextrin; (2-hydroxypropyl)-beta-cyclodextrin; HYDROXYPROPYL-β-CYCLODEXTRIN; beta-Cyclodextrin, 2-hydroxypropyl ether CAS
Hubei YuanCheng GongChuang Technology Co.Ltd [2015-06-03 11:52:39 ]
Methyl 2-cyclopentanonecarboxylate Name Methyl 2-cyclopentanonecarboxylate Synonym Methyl 2-oxocyclopentanecarboxylate; 2-Carbomethoxycyclopentanone; Cyclopentanone-2-carboxylic acid methyl ester; Methyl-2-oxocyclopentane carboxylate; ethyl (4-methylphenyl)acetate; methyl (1R)-2-
Hubei YuanCheng GongChuang Technology Co.Ltd [2015-06-03 11:48:06 ]
2-Methoxyethoxymethyl chloride Name 2-Methoxyethoxymethyl chloride Synonym 2-Methoxyethoxymethyl chloride; 1-chloro-2,5-dioxahexane; Alcoxyethoxymethylchloride; Alcoxyethoxylmethylchloride; 1-(chloromethoxy)-2-methoxyethane; 1-(pyridin-2-ylsulfonyl)-1H-benzotriazole; 1-Methoxy-2-
Hubei YuanCheng GongChuang Technology Co.Ltd [2015-06-03 11:46:58 ]
Brexpiprazole (OPC-34712) is a close structural analog of aripiprazole and shares some of its pharmacological properties. Similarly to aripiprazole, brexpiprazole exhibits partial agonism of D2R and an enhanced affinity for specific serotonin receptors (e g., 5-HT1A, 5-HT2A and 5
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 11:43:47 ]
2-Cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-methanol Name 2-Cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-methanol Synonym 2-cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-methanol;2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinemethanol;PT-1;N-2 2-CYCLOPROPYL-4-(4-FLUOROPHENYL) -QUINOLYL-3-M
Hubei YuanCheng GongChuang Technology Co.Ltd [2015-06-03 11:42:24 ]
Ispinesib is a potent, allosteric, reversible, and specific inhibitor of KSP, which changes the binding property of KSP to microtubules and disturbs its movement by inhibiting ADP release without altering the release of the KSP-ADP complex from the microtubule. Ispinesib shows po
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 11:40:58 ]
classical queen sofa sleeper High-resiliency foam cushions wrapped in thick poly fiber Tight back cushions and loose seat cushions Pillows with soft polyfill Decorative pillows included Cotton upholstery; Cotton /rayon and polyester pillows Width 76'' Depth 43'' Height 47'' Weigh
Shenzhen Ekar Furniture CO.,LTD [2015-06-03 11:37:54 ]
Classic Wooden Fabric Sofa Design, Living Room Sofa High-resiliency foam cushions wrapped in thick poly fiber Tight back cushions and loose seat cushions Pillows with soft polyfill Decorative pillows included Cotton upholstery; Cotton /rayon and polyester pillows Dimensions Singl
Shenzhen Ekar Furniture CO.,LTD [2015-06-03 11:36:41 ]
