AMB-FUBINACA is an indazole-based synthetic cannabinoid that is a potent agonist for the cannabinoid receptors, with Kᵢ values of 10.04 nM at CB₁ and 0.786 nM at CB₂ and EC₅₀ values of 0.5433 nM at CB₁ and 0.1278 nM at CB₂, and has been sold online as a designer dru
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FUB-APINACA is an indazole-based synthetic cannabinoid that is presumed to be a potent agonist of the CB₁ receptor and has been sold online as a designer drug. It is an analog of APINACA and 5F-APINACA where the pentyl chain has been replaced with fluorobenzyl
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5F-ADB (also known as 5F-MDMB-PINACA) is an indazole-based synthetic cannabinoid from the indazole-3-carboxamide family, which has been used as an active ingredient in synthetic cannabis products and has been sold online as a designer drug.[1] 5F-ADB is a potent agonist of the CB
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Purpose The aim of the present study was to evaluate the cytotoxicity of five synthetic cannabinoids in two cell lines, for which both reference standards and herbal blends were available. Methods An in-house smoking device was developed to produce smoke condensates. The cell via
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