K8 Wrinkle removal skin tightening aesthetic beauty equipment ZKKL-K8 adopts the EMOS high-technology, anti-aging efficient equipment, long term effect. We use alternating electric field and capacitive field for heat energy produce. The dermis tissue will be heated evenly, the wh
Wuhan CAS Keli Electrooptical Technology Co.Ltd [2015-06-06 15:01:50 ]
Fluorocytosine CAS 2022-85-7 MF C4H4FN3O MW 129.09 EINECS 217-968-7 mp 298-300 °C (dec.)(lit.) storage temp. 2-8°C Water Solubility 1.5g/100mL (25 oC) Sensitive Light Sensitive Chemical Properties White Crystalline Solid Usage 5-FC is a toxic antifungal/antimicrobial agent Puri
Hubei YuanCheng GongChuang Technology Co.Ltd [2015-06-03 15:13:28 ]
Hydrocortisone acetate Name Hydrocortisone acetate Synonym (11beta)-21-(Acetoxy)-11,17,21-trihydroxypregna-1,4-diene-3,20-dione;11,17-Dihydroxy-3,20-dioxopregn-4-en-21-yl acetate;11-beta,17-alpha-dihydroxy-21-acetoxypregesterone;11beta17alpha-Dihydroxy-21-acetoxypregesterone;17-a
Hubei YuanCheng GongChuang Technology Co.Ltd [2015-06-03 14:18:00 ]
Dabrafenib (GSK2118436) is a mutant BRAFV600 specific inhibitor with IC50 of 0.8 nM, with 4- and 6-fold less potency against B-Raf(wt) and c-Raf, respectively.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 13:40:24 ]
Alogliptin benzoate(SYR 322) is a potent, selective inhibitor of DPP-4 with IC50 of <10 nM, exhibits greater than 10,000-fold selectivity over DPP-8 and DPP-9.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 13:05:15 ]
Brexpiprazole (OPC-34712) is a close structural analog of aripiprazole and shares some of its pharmacological properties. Similarly to aripiprazole, brexpiprazole exhibits partial agonism of D2R and an enhanced affinity for specific serotonin receptors (e g., 5-HT1A, 5-HT2A and 5
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 11:43:47 ]
AEE788(NVP-AEE 788) is a potent inhibitor of EGFR and HER2/ErbB2 with IC50 of 2 nM and 6 nM, less potent to VEGFR2/KDR, c-Abl, c-Src, and Flt-1, does not inhibit Ins-R, IGF-1R, PKCα and CDK1.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 11:24:23 ]
Felbamate (FBM) is a potent nonsedative anticonvulsant whose clinical effect may be related to the inhibition of N-methyl-D-aspartate (NMDA) .
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 11:15:50 ]
Pexidartinib(PLX-3397) is a small-molecule receptor tyrosine kinase (RTK) inhibitor of KIT, CSF1R and FLT3 with potential antineoplastic activity.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 11:12:36 ]
AI-10-49 is a protein-protein interaction inhibitor that selectively binds to CBFβ-SMMHC and disrupts its binding to RUNX1 with a FRET IC50 of 0.26 uM.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 10:58:04 ]
Evacetrapib (LY2484595) is a potent and selective inhibitor of CETP with IC50 of 5.5 nM, elevates HDL cholesterol without increases in aldosterone or blood pressure.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 10:53:10 ]
Afatinib (BIBW2992) irreversibly inhibits EGFR/HER2 including EGFR(wt) , EGFR(L858R) , EGFR(L858R/T790M) and HER2 with IC50 of 0.5 nM, 0.4 nM, 10 nM and 14 nM in cell-free assays, respectively; 100-fold more active against Gefitinib-resistant L858R-T790M EGFR mutant.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 10:42:45 ]
Afatinib (BIBW2992) irreversibly inhibits EGFR/HER2 including EGFR(wt), EGFR(L858R), EGFR(L858R/T790M) and HER2 with IC50 of 0.5 nM, 0.4 nM, 10 nM and 14 nM, respectively; 100-fold more active against Gefitinib-resistant L858R-T790M EGFR mutant.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 10:39:48 ]
Adrafinil (CRL-40028, Olmifon), prodrug of modafinil, is a mild central nervous system stimulant drug used to relieve excessive sleepiness and inattention, Adrafinil is believed to serve as an alpha-1 adrenoceptor agonist.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 10:35:50 ]
L-Alpha glycerylphosphorylcholine (alpha-GPC, choline alfoscerate) is a natural choline compound found in the brain and in milk. It is also a parasympathomimetic acetylcholine precursor which may have potential for the treatment of Alzheimer's disease
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 10:29:47 ]
AP-26113 exhibited approx 100-fold selectivity for ALK-positive lines compared with a approx 10-fold selectivity for PF-1066. At the highest doses tested, strong regressions were achieved with AP-26113, but not PF-1066 .AP-26113 inhibited the tumor growth at 25 mg/kg in ALCL and
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 10:19:12 ]
Asenapine maleate(Org 5222 maleate) inhibits adrenergic receptor (α1, α2A, α2B, α2C) with Ki of 0.25-1.2 nM and also inhibits 5-HT receptor (1A, 1B, 2A, 2B, 2C, 5A, 6, 7) with Ki of 0.03-4.0 nM.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 10:14:21 ]
AT13387 is a synthetic, orally bioavailable, small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity. Hsp90 inhibitor AT13387 selectively binds to Hsp90, thereby inhibiting its chaperone function and promoting the degradation of oncogenic
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 10:10:11 ]
AT9283 is a small molecule a multi-targeted inhibitor with IC50s of 4, 1.2, 1.1 and approximate 3 nM for Bcr-Abl(T3151), JAK2 and JAK3, Aurora A and Aurora B, respectively.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 10:06:37 ]
AVL-292 is a covalent, highly selective, orally active small molecule inhibitor of Btk with IC50 value of 0.5 nM; >1400-fold selectivity over the other kinases assayed.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 10:01:57 ]
